ID ARMX6_RAT Reviewed; 301 AA.
AC Q66HF0;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 24-JAN-2024, entry version 99.
DE RecName: Full=Protein ARMCX6;
GN Name=Armcx6;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May regulate the dynamics and distribution of mitochondria in
CC neural cells. {ECO:0000250|UniProtKB:Q8K3A6}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q8K3A6}.
CC Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8BHS6}; Single-
CC pass membrane protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the eutherian X-chromosome-specific Armcx
CC family. {ECO:0000305}.
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DR EMBL; BC081893; AAH81893.1; -; mRNA.
DR RefSeq; NP_001007758.1; NM_001007757.1.
DR RefSeq; XP_008771647.1; XM_008773425.2.
DR RefSeq; XP_017457600.1; XM_017602111.1.
DR RefSeq; XP_017457601.1; XM_017602112.1.
DR RefSeq; XP_017457602.1; XM_017602113.1.
DR AlphaFoldDB; Q66HF0; -.
DR STRING; 10116.ENSRNOP00000035673; -.
DR PhosphoSitePlus; Q66HF0; -.
DR PaxDb; 10116-ENSRNOP00000035673; -.
DR Ensembl; ENSRNOT00000029807.6; ENSRNOP00000035673.4; ENSRNOG00000037707.4.
DR Ensembl; ENSRNOT00055024985; ENSRNOP00055020420; ENSRNOG00055014570.
DR Ensembl; ENSRNOT00060037659; ENSRNOP00060031052; ENSRNOG00060021748.
DR Ensembl; ENSRNOT00065009031; ENSRNOP00065006431; ENSRNOG00065005982.
DR GeneID; 363496; -.
DR KEGG; rno:363496; -.
DR UCSC; RGD:1359303; rat.
DR AGR; RGD:1359303; -.
DR CTD; 54470; -.
DR RGD; 1359303; Armcx6.
DR eggNOG; ENOG502RP3G; Eukaryota.
DR GeneTree; ENSGT00940000163042; -.
DR HOGENOM; CLU_037187_0_1_1; -.
DR InParanoid; Q66HF0; -.
DR OMA; FIQGKMW; -.
DR OrthoDB; 5262111at2759; -.
DR PhylomeDB; Q66HF0; -.
DR TreeFam; TF335652; -.
DR PRO; PR:Q66HF0; -.
DR Proteomes; UP000002494; Chromosome X.
DR Bgee; ENSRNOG00000037707; Expressed in pancreas and 19 other cell types or tissues.
DR Genevisible; Q66HF0; RN.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR InterPro; IPR006911; ARM-rpt_dom.
DR PANTHER; PTHR15712; ARMADILLO REPEAT CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15712:SF6; PROTEIN ARMCX6; 1.
DR Pfam; PF04826; Arm_2; 1.
PE 2: Evidence at transcript level;
KW Membrane; Mitochondrion; Mitochondrion outer membrane; Reference proteome;
KW Signal-anchor; Transmembrane; Transmembrane helix.
FT CHAIN 1..301
FT /note="Protein ARMCX6"
FT /id="PRO_0000191376"
FT TOPO_DOM 1..7
FT /note="Mitochondrial intermembrane"
FT /evidence="ECO:0000250|UniProtKB:Q8BHS6"
FT TRANSMEM 8..25
FT /note="Helical; Signal-anchor"
FT /evidence="ECO:0000255"
FT TOPO_DOM 26..301
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250|UniProtKB:Q8BHS6"
FT REGION 1..6
FT /note="Mitochondrion outer membrane (MOM)-targeting
FT sequence"
FT /evidence="ECO:0000305"
FT REGION 26..36
FT /note="Mitochondrion outer membrane (MOM)-targeting
FT sequence"
FT /evidence="ECO:0000305"
FT REGION 70..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 301 AA; 33374 MW; 8C71EA397C990643 CRC64;
MGRAREMGWM AAGLMIGAGA CYCMYKLTMG RDEGNELENE EEDEWDDEQD LDEEEADIWF
DFTAMARPWS EDGEWDEPGA PGGTEDRRSG GGKANRAHPT KQRPFPYEHK NIWGVQSFQT
FPCALNLTKC AFSQGKKMFT ESTIAGFSLT HNVSRHLSSL SVVGSRSPTP QPTVREKALD
VPEHPNSSIE NQDQIKMYID EVCRDAVFCC CKSFLQQAGL GLLISMTVIN NMLAKSLSDP
KFPLLSEGSG CAKVQGLEAQ MSLPEKPVLA EEVLAAQMLF SFMCLFTRSG SREMLVEAIS
P
//
