ID   ATG17_ASPOR             Reviewed;         550 AA.
AC   Q2UFN7;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   RecName: Full=Autophagy-related protein 17;
GN   Name=atg17; ORFNames=AO090026000134;
OS   Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=510516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42149 / RIB 40;
RX   PubMed=16372010; DOI=10.1038/nature04300;
RA   Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA   Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA   Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA   Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA   Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA   Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA   Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA   Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA   Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA   Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA   Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA   Kikuchi H.;
RT   "Genome sequencing and analysis of Aspergillus oryzae.";
RL   Nature 438:1157-1161(2005).
CC   -!- FUNCTION: Autophagy-specific protein that functions in response to
CC       autophagy-inducing signals as a scaffold to recruit other ATG proteins
CC       to organize pre-autophagosomal structure (PAS) formation. Modulates the
CC       timing and magnitude of the autophagy response, such as the size of the
CC       sequestering vesicles. Plays particularly a role in pexophagy and
CC       nucleophagy (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Preautophagosomal
CC       structure membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATG17 family. {ECO:0000305}.
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DR   EMBL; AP007159; BAE59628.1; -; Genomic_DNA.
DR   RefSeq; XP_001821630.1; XM_001821578.1.
DR   AlphaFoldDB; Q2UFN7; -.
DR   SMR; Q2UFN7; -.
DR   STRING; 510516.Q2UFN7; -.
DR   EnsemblFungi; BAE59628; BAE59628; AO090026000134.
DR   GeneID; 5993658; -.
DR   KEGG; aor:AO090026000134; -.
DR   VEuPathDB; FungiDB:AO090026000134; -.
DR   HOGENOM; CLU_028356_0_0_1; -.
DR   OMA; THVWRAN; -.
DR   OrthoDB; 1940609at2759; -.
DR   Proteomes; UP000006564; Chromosome 3.
DR   GO; GO:0034045; C:phagophore assembly site membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   InterPro; IPR007240; Atg17.
DR   InterPro; IPR045326; ATG17-like_dom.
DR   PANTHER; PTHR28005; AUTOPHAGY-RELATED PROTEIN 17; 1.
DR   PANTHER; PTHR28005:SF1; AUTOPHAGY-RELATED PROTEIN 17; 1.
DR   Pfam; PF04108; ATG17_like; 1.
PE   3: Inferred from homology;
KW   Autophagy; Coiled coil; Cytoplasm; Membrane; Reference proteome.
FT   CHAIN           1..550
FT                   /note="Autophagy-related protein 17"
FT                   /id="PRO_0000317981"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          204..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          492..527
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          317..350
FT                   /evidence="ECO:0000255"
FT   COILED          427..457
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   550 AA;  60484 MW;  3D3AEE60D5696A2C CRC64;
     MSDSESSAIS NNASDLNPSP GQENSMPQLE TLISHLVAAK RSLSSINHVW RANEIVTAAR
     SALEESVVVS ARTGFLRRGL NNQLRLLYSV RTEVQEVSLR GRSEFATVLK SLDVADARLR
     KTLDLLRDTI VHASFRPEGE ESKTLHDFVD ERGVGELHTT LKRSIDRTNA AQADLESSNR
     AFDDELQSIK EALGNYRAAT QLASSRTSAS SSSPSTSNDS LPSLSSIPSM LHSLEMHAQE
     MANLLESLVR HFDLCVTAVK HTEGGGAAAR SITGDVPATV HVNGRVGPNI EEGINANLNA
     PLDPLSNSEY QEMVSVLIKD AAEAEDVVME IQDRIGEMET VLENVLAQRD SVLSVYNATT
     SVFKHLSTLA STRLSGYIAE AHSFTRVWHE EYEQIQSGLA DLSDLNTLYD GFLEAYDGLI
     LEVARRRQVR HRVEKVLRDA KQKLDQLYEE DVNARETFRV EQGDYLPSDI WPGIGREPMR
     IEFRRISGGN LKGIAAEPPD QDAAAAEPKQ EARAVSSGDV GEDGEVIPEL PKALVEEAIA
     RFNARMRHLP
//