ID B0C5U4_ACAM1 Unreviewed; 729 AA.
AC B0C5U4;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN OrderedLocusNames=AM1_4988 {ECO:0000313|EMBL:ABW29956.1};
OS Acaryochloris marina (strain MBIC 11017).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Acaryochloridales;
OC Acaryochloridaceae; Acaryochloris.
OX NCBI_TaxID=329726 {ECO:0000313|EMBL:ABW29956.1, ECO:0000313|Proteomes:UP000000268};
RN [1] {ECO:0000313|EMBL:ABW29956.1, ECO:0000313|Proteomes:UP000000268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MBIC 11017 {ECO:0000313|Proteomes:UP000000268};
RX PubMed=18252824; DOI=10.1073/pnas.0709772105;
RA Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J.,
RA Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D.,
RA Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y.,
RA Taylor H.L., Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M.,
RA Blankenship R.E., Touchman J.W.;
RT "Niche adaptation and genome expansion in the chlorophyll d-producing
RT cyanobacterium Acaryochloris marina.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008).
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DR EMBL; CP000828; ABW29956.1; -; Genomic_DNA.
DR RefSeq; WP_012165228.1; NC_009925.1.
DR AlphaFoldDB; B0C5U4; -.
DR STRING; 329726.AM1_4988; -.
DR KEGG; amr:AM1_4988; -.
DR eggNOG; COG1672; Bacteria.
DR HOGENOM; CLU_021307_0_0_3; -.
DR OrthoDB; 5522963at2; -.
DR Proteomes; UP000000268; Chromosome.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR024983; CHAT_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR Pfam; PF14516; AAA_35; 1.
DR Pfam; PF12770; CHAT; 1.
DR Pfam; PF13676; TIR_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000268}.
FT DOMAIN 219..358
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 177..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 729 AA; 81769 MW; DBEF4DA3736E9FE5 CRC64;
MRKILILAAN PKNTNQLRLD EEVREIQEGL QRSRSRDQFE IVSRWAVRPS DLRRALLDYE
PQIVHFCGHG AGAEGLALEN NAGQIKLVTG KALGGLFKLV QANVECVLLN ACYSEAQSKA
IHKYISYVIG MSNAIGDRAA IEFAVGFYDG LGADRSYEDA FEFGLSAIAL EGIDETATPK
LKSPGPGSSP NSVQRINPSS AQKPESENKT ANNPLSGEGK ARIFISYKRD AVPDEQLALA
IYQHLGQSHE VFIDQSMAVG TKWAEKIERE LRQSDFLITL LSASAVGSEM VQGEVETANR
LGSELGKPAI LPVRVNYREP FTYPLSAYLN PINWAFWEQS EDTPQLLAEL ERAIAGESLS
IASDRAKQDL VQLPTADKAE IPQPLPSAQP PTLEMPEGSM DPESQFYVER QGDQIALAAI
QRQGVTVTIK GPRQMGKSSL LLKTVDQAIQ ADKRVAYIDF QLFDDAALGD ADRFYQQFCL
TITEQLELPN RIEDFWQDEL GNNQRCTRYM QTYVLRELKH PFVLAMDEVD RIFDRKFRSD
FFAMLRNWHN NRGLPLPAMK VWKQFDLVLV TATEPYHLIA DLHQSPFNVG EVISLKDFTA
AQVADLNQRH GSPLTAEQER ALFALLNGHP YLIRKALYLV ASGQKSMDQV LAKADRDDGP
FGDHLRYHLF RIYDRPELVQ GMLGAVQKNR CEDERIVRLL CAAGLIRQEG KAELPRCQLY
GDYFKAHLE
//
