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Database: UniProt
Entry: B0CE02_ACAM1
LinkDB: B0CE02_ACAM1
Original site: B0CE02_ACAM1 
ID   B0CE02_ACAM1            Unreviewed;       417 AA.
AC   B0CE02;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   28-MAR-2018, entry version 69.
DE   RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase 2 {ECO:0000256|PIRNR:PIRNR000447};
DE            EC=2.3.1.179 {ECO:0000256|PIRNR:PIRNR000447};
GN   Name=fabF {ECO:0000313|EMBL:ABW30476.1};
GN   OrderedLocusNames=AM1_5522 {ECO:0000313|EMBL:ABW30476.1};
OS   Acaryochloris marina (strain MBIC 11017).
OC   Bacteria; Cyanobacteria; Synechococcales; Acaryochloridaceae;
OC   Acaryochloris.
OX   NCBI_TaxID=329726 {ECO:0000313|EMBL:ABW30476.1, ECO:0000313|Proteomes:UP000000268};
RN   [1] {ECO:0000313|EMBL:ABW30476.1, ECO:0000313|Proteomes:UP000000268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MBIC 11017 {ECO:0000313|Proteomes:UP000000268};
RX   PubMed=18252824; DOI=10.1073/pnas.0709772105;
RA   Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J.,
RA   Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D.,
RA   Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M.,
RA   Shimada Y., Taylor H.L., Tomo T., Tsuchiya T., Wang Z.T., Raymond J.,
RA   Mimuro M., Blankenship R.E., Touchman J.W.;
RT   "Niche adaptation and genome expansion in the chlorophyll d-producing
RT   cyanobacterium Acaryochloris marina.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008).
CC   -!- FUNCTION: Catalyzes the condensation reaction of fatty acid
CC       synthesis by the addition to an acyl acceptor of two carbons from
CC       malonyl-ACP. {ECO:0000256|PIRNR:PIRNR000447}.
CC   -!- CATALYTIC ACTIVITY: (Z)-hexadec-11-enoyl-[acyl-carrier-protein] +
CC       malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-
CC       carrier-protein] + CO(2) + [acyl-carrier-protein].
CC       {ECO:0000256|PIRNR:PIRNR000447}.
CC   -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC       {ECO:0000256|PIRNR:PIRNR000447}.
CC   -!- SIMILARITY: Belongs to the beta-ketoacyl-ACP synthases family.
CC       {ECO:0000256|PIRNR:PIRNR000447, ECO:0000256|RuleBase:RU003694}.
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DR   EMBL; CP000828; ABW30476.1; -; Genomic_DNA.
DR   RefSeq; WP_012165706.1; NC_009925.1.
DR   ProteinModelPortal; B0CE02; -.
DR   STRING; 329726.AM1_5522; -.
DR   PRIDE; B0CE02; -.
DR   EnsemblBacteria; ABW30476; ABW30476; AM1_5522.
DR   KEGG; amr:AM1_5522; -.
DR   eggNOG; ENOG4105C0Q; Bacteria.
DR   eggNOG; COG0304; LUCA.
DR   HOGENOM; HOG000060166; -.
DR   KO; K09458; -.
DR   OMA; PFFVPKI; -.
DR   OrthoDB; POG091H018O; -.
DR   UniPathway; UPA00094; -.
DR   Proteomes; UP000000268; Chromosome.
DR   GO; GO:0033817; F:beta-ketoacyl-acyl-carrier-protein synthase II activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR017568; 3-oxoacyl-ACP_synth-2.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR   InterPro; IPR016039; Thiolase-like.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   PIRSF; PIRSF000447; KAS_II; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR03150; fabF; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|PIRNR:PIRNR000447};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000268};
KW   Fatty acid biosynthesis {ECO:0000256|PIRNR:PIRNR000447};
KW   Fatty acid metabolism {ECO:0000256|PIRNR:PIRNR000447};
KW   Lipid biosynthesis {ECO:0000256|PIRNR:PIRNR000447};
KW   Lipid metabolism {ECO:0000256|PIRNR:PIRNR000447};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000268};
KW   Transferase {ECO:0000256|PIRNR:PIRNR000447,
KW   ECO:0000256|RuleBase:RU003694}.
FT   DOMAIN        9    417       PKS_KS. {ECO:0000259|SMART:SM00825}.
FT   ACT_SITE    167    167       {ECO:0000256|PIRSR:PIRSR000447-1}.
SQ   SEQUENCE   417 AA;  43777 MW;  341B49E46D0A7DEA CRC64;
     MTNLEPKRVV ITGLGAITPL GNTLSEYWDG LLAGRSGIGP VTRFDAAKHA CRIAGEVKGF
     DPQDYMDRKD AKRMDRFAQF AVSASKQALA DANFTIDDSN ANDIGIIIGT GIGGLKVLED
     QQEIYLTKGP DRCSPFMIPM MIANMAAGLT AIHVGAKGPN SCSVTACAAG SNAIGDAFRF
     VQRGYTKAMI CGGTEAAVTP LSMAGFAACR ALSTRNDEPT KASRPFDKDR DGFVLGEGVG
     ILIIEELEHA LARGAKIYAE LIGYGVTCDA HHMTSPSPGG VGAARAIELC LKDANLTPDQ
     ISYINAHGTS TNANDTTETA AIKHAIGDNA YRVAISSTKS MTGHLLGGSG GIEAVATAMA
     IANDQVPPTI NLDNPDEGCD LDYIPHTSRE LTVDVALSNS FGFGGHNVTL AFRKYVD
//
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