ID   B0DNX4_LACBS            Unreviewed;       340 AA.
AC   B0DNX4;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   RecName: Full=Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha {ECO:0000256|ARBA:ARBA00040965};
DE            EC=2.5.1.58 {ECO:0000256|ARBA:ARBA00012702};
DE            EC=2.5.1.59 {ECO:0000256|ARBA:ARBA00012700};
DE   AltName: Full=CAAX farnesyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00043086};
DE   AltName: Full=FTase-alpha {ECO:0000256|ARBA:ARBA00042436};
DE   AltName: Full=Ras proteins prenyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00041392};
DE   AltName: Full=Type I protein geranyl-geranyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00043219};
GN   ORFNames=LACBIDRAFT_191455 {ECO:0000313|EMBL:EDR03801.1};
OS   Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver)
OS   (Laccaria laccata var. bicolor).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Hydnangiaceae; Laccaria.
OX   NCBI_TaxID=486041 {ECO:0000313|Proteomes:UP000001194};
RN   [1] {ECO:0000313|EMBL:EDR03801.1, ECO:0000313|Proteomes:UP000001194}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 / ATCC MYA-4686 {ECO:0000313|Proteomes:UP000001194};
RX   PubMed=18322534; DOI=10.1038/nature06556;
RA   Martin F., Aerts A., Ahren D., Brun A., Danchin E.G.J., Duchaussoy F.,
RA   Gibon J., Kohler A., Lindquist E., Pereda V., Salamov A., Shapiro H.J.,
RA   Wuyts J., Blaudez D., Buee M., Brokstein P., Canbaeck B., Cohen D.,
RA   Courty P.E., Coutinho P.M., Delaruelle C., Detter J.C., Deveau A.,
RA   DiFazio S., Duplessis S., Fraissinet-Tachet L., Lucic E., Frey-Klett P.,
RA   Fourrey C., Feussner I., Gay G., Grimwood J., Hoegger P.J., Jain P.,
RA   Kilaru S., Labbe J., Lin Y.C., Legue V., Le Tacon F., Marmeisse R.,
RA   Melayah D., Montanini B., Muratet M., Nehls U., Niculita-Hirzel H.,
RA   Oudot-Le Secq M.P., Peter M., Quesneville H., Rajashekar B., Reich M.,
RA   Rouhier N., Schmutz J., Yin T., Chalot M., Henrissat B., Kuees U.,
RA   Lucas S., Van de Peer Y., Podila G.K., Polle A., Pukkila P.J.,
RA   Richardson P.M., Rouze P., Sanders I.R., Stajich J.E., Tunlid A.,
RA   Tuskan G., Grigoriev I.V.;
RT   "The genome of Laccaria bicolor provides insights into mycorrhizal
RT   symbiosis.";
RL   Nature 452:88-92(2008).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the protein prenyltransferase subunit alpha
CC       family. {ECO:0000256|ARBA:ARBA00006734}.
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DR   EMBL; DS547122; EDR03801.1; -; Genomic_DNA.
DR   RefSeq; XP_001885654.1; XM_001885619.1.
DR   AlphaFoldDB; B0DNX4; -.
DR   STRING; 486041.B0DNX4; -.
DR   GeneID; 6081284; -.
DR   KEGG; lbc:LACBIDRAFT_191455; -.
DR   HOGENOM; CLU_026582_1_1_1; -.
DR   InParanoid; B0DNX4; -.
DR   OrthoDB; 20949at2759; -.
DR   Proteomes; UP000001194; Unassembled WGS sequence.
DR   GO; GO:0008318; F:protein prenyltransferase activity; IEA:InterPro.
DR   Gene3D; 1.25.40.120; Protein prenylyltransferase; 1.
DR   InterPro; IPR002088; Prenyl_trans_a.
DR   PANTHER; PTHR11129; PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT; 1.
DR   PANTHER; PTHR11129:SF1; PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA; 1.
DR   Pfam; PF01239; PPTA; 5.
DR   SUPFAM; SSF48439; Protein prenylyltransferase; 1.
DR   PROSITE; PS51147; PFTA; 4.
PE   3: Inferred from homology;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Prenyltransferase {ECO:0000256|ARBA:ARBA00022602};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001194};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022602}.
SQ   SEQUENCE   340 AA;  39625 MW;  0AD31DC46BB51B51 CRC64;
     MSTPALQEEK EEPVIPLFAE RPEWVDVVPL EQYEGVNPLA PILYSPVYKD ATNYFRGIVK
     VGEKSQRVLE LTEAVIRLNP AHYSAWQYRY ETLLSINAPL DVELKLIDEL AVKYLKTYQV
     WHHRRLLLTI TRKPAQELDF ITRSLTADTK NYHTWSYRQW LLAYFNDEDE LWTGELDFVD
     AMLAQDVRNN SAWHHRFFVV WGCGVREGEG DRERVYTREL TYVKQNISLA PNNLSAWNYL
     RGIMEHSKTP FASVKAFVRP YTLPIDPTSV DIVDLENPPP TKGANLPCPS AIEFLADVYE
     LEKNTLEAIE LWTSLANTHD VIRKKYWEHR IRDALEASRI
//