ID B0DWH5_LACBS Unreviewed; 507 AA.
AC B0DWH5;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Guanine nucleotide-binding protein alpha-4 subunit {ECO:0000313|EMBL:EDR01047.1};
GN ORFNames=LACBIDRAFT_333606 {ECO:0000313|EMBL:EDR01047.1};
OS Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver)
OS (Laccaria laccata var. bicolor).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hydnangiaceae; Laccaria.
OX NCBI_TaxID=486041 {ECO:0000313|Proteomes:UP000001194};
RN [1] {ECO:0000313|EMBL:EDR01047.1, ECO:0000313|Proteomes:UP000001194}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 / ATCC MYA-4686 {ECO:0000313|Proteomes:UP000001194};
RX PubMed=18322534; DOI=10.1038/nature06556;
RA Martin F., Aerts A., Ahren D., Brun A., Danchin E.G.J., Duchaussoy F.,
RA Gibon J., Kohler A., Lindquist E., Pereda V., Salamov A., Shapiro H.J.,
RA Wuyts J., Blaudez D., Buee M., Brokstein P., Canbaeck B., Cohen D.,
RA Courty P.E., Coutinho P.M., Delaruelle C., Detter J.C., Deveau A.,
RA DiFazio S., Duplessis S., Fraissinet-Tachet L., Lucic E., Frey-Klett P.,
RA Fourrey C., Feussner I., Gay G., Grimwood J., Hoegger P.J., Jain P.,
RA Kilaru S., Labbe J., Lin Y.C., Legue V., Le Tacon F., Marmeisse R.,
RA Melayah D., Montanini B., Muratet M., Nehls U., Niculita-Hirzel H.,
RA Oudot-Le Secq M.P., Peter M., Quesneville H., Rajashekar B., Reich M.,
RA Rouhier N., Schmutz J., Yin T., Chalot M., Henrissat B., Kuees U.,
RA Lucas S., Van de Peer Y., Podila G.K., Polle A., Pukkila P.J.,
RA Richardson P.M., Rouze P., Sanders I.R., Stajich J.E., Tunlid A.,
RA Tuskan G., Grigoriev I.V.;
RT "The genome of Laccaria bicolor provides insights into mycorrhizal
RT symbiosis.";
RL Nature 452:88-92(2008).
CC -!- SIMILARITY: Belongs to the G-alpha family.
CC {ECO:0000256|ARBA:ARBA00005804}.
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DR EMBL; DS547143; EDR01047.1; -; Genomic_DNA.
DR RefSeq; XP_001888266.1; XM_001888231.1.
DR AlphaFoldDB; B0DWH5; -.
DR STRING; 486041.B0DWH5; -.
DR GeneID; 6083957; -.
DR KEGG; lbc:LACBIDRAFT_333606; -.
DR HOGENOM; CLU_014184_1_1_1; -.
DR InParanoid; B0DWH5; -.
DR OrthoDB; 1864818at2759; -.
DR Proteomes; UP000001194; Unassembled WGS sequence.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF302; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-8 SUBUNIT-RELATED; 1.
DR Pfam; PF00503; G-alpha; 2.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001194};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 507 AA; 56718 MW; 2BE94ACE69A9CC5C CRC64;
MIHHHLTVTN QITHLGSQRE QIRRTQPYTL GKKETSPNPE TSSHQTVASN AWHPHQDDPI
SAALKPSPME ASVSSQIDDD LREERERLEK KKGDVKLLLL GQAESGKSTL PKQFQLMYKP
TSMDQERASW TAVIYFNVVR SLKHILATLE AWDDTLDEDA EAQPTSTDDS QSIIPKKARG
NGIADQPSPS TSLLTGSIIQ GSPSSLMPSE AGGSHSHSMK EGGALQIANL RRRLSPLVAA
DAQLADRLSG GISVSGSGKG GVFVRSGWQA RTIENALGKI KQKCPSAESE KKTREIEPQE
PQDPLDIREL WHHPTVKGLI AKRKRKLDEW SEFFLKNITR VASPDYVPSI DDILHARIQT
MGVAEHIFDV NIHGKSVTWH LFDVGGARGQ RHSWVPYFDD TNAIIFVAPN VHLVLFLNKT
DLLKAKLDTG LKVRKYIMSF GDRSNDYETV VQYFRAHFLQ VHRRNNENRQ VLYTHFTSVV
DTKATQRIIG NVRDSIFRGY LQSAALV
//
