ID B0JMX7_MICAN Unreviewed; 537 AA.
AC B0JMX7;
DT 18-MAR-2008, integrated into UniProtKB/TrEMBL.
DT 18-MAR-2008, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Mechanosensitive ion channel {ECO:0000313|EMBL:BAG00141.1};
GN OrderedLocusNames=MAE_03190 {ECO:0000313|EMBL:BAG00141.1};
OS Microcystis aeruginosa (strain NIES-843 / IAM M-2473).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Microcystaceae; Microcystis.
OX NCBI_TaxID=449447 {ECO:0000313|EMBL:BAG00141.1, ECO:0000313|Proteomes:UP000001510};
RN [1] {ECO:0000313|EMBL:BAG00141.1, ECO:0000313|Proteomes:UP000001510}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-843 {ECO:0000313|EMBL:BAG00141.1,
RC ECO:0000313|Proteomes:UP000001510};
RX PubMed=18192279; DOI=10.1093/dnares/dsm026;
RA Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M.,
RA Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A.,
RA Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M.,
RA Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M.;
RT "Complete genomic structure of the bloom-forming toxic cyanobacterium
RT Microcystis aeruginosa NIES-843.";
RL DNA Res. 14:247-256(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; AP009552; BAG00141.1; -; Genomic_DNA.
DR AlphaFoldDB; B0JMX7; -.
DR STRING; 449447.MAE_03190; -.
DR PaxDb; 449447-MAE_03190; -.
DR EnsemblBacteria; BAG00141; BAG00141; MAE_03190.
DR KEGG; mar:MAE_03190; -.
DR eggNOG; COG0668; Bacteria.
DR HOGENOM; CLU_032048_1_0_3; -.
DR Proteomes; UP000001510; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR045275; MscS_archaea/bacteria_type.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR PANTHER; PTHR30221:SF18; SLL0590 PROTEIN; 1.
DR PANTHER; PTHR30221; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 339..404
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 418..499
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 537 AA; 60317 MW; 5D262B684FA895AA CRC64;
MIAAQNNPAK QGQETPLETL GEVFPVMLDN QELFTIRQGI GSFSAQERAK SITTRIEKIA
DDDALSPEDL TIKIDPEDKN PSIILGDTVI ATITSKDAKL HSVSQEVLAE RALAKIKAAI
VRYRQERQPD NLLKDATLTV SATLATVLIF WVIIFISSRV FPQIQRLITS LVPGVVFQNF
EIISSQTIGI CCLRVLQFIR TLIILTILYF YLTFVLRLFP WTRKFGDGFL QYFFSALEVI
SQEIAKYLPN IFIILLIVFI THYLLRAIKP FFTGLERENL VIHGFYPDWA KPTYNLLSLL
IIALAIVIAF PYLPGFNSPA FQGVSVFLGV LFSLGSTSAI ANVVGGIILI YTRSFQLGDK
ISIGDVIGDV IEKGLLVTRI RTPANRIITI PNSSLLNTNV INFSVSQREF KQPLILQTTV
TLGYDLPWRK VHTTLKEAAL ATKFIVSEPA PFVLQTSLDD FYVSYQLNAY TDHPSKMVYI
YSELHQNIQD KCNEVGIEIM SPHYKALRDG NHSTIPENYL PEDYQSPAFG IQSNPQK
//
