ID B0JNA5_MICAN Unreviewed; 387 AA.
AC B0JNA5;
DT 18-MAR-2008, integrated into UniProtKB/TrEMBL.
DT 18-MAR-2008, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0000256|ARBA:ARBA00011975};
DE EC=2.1.1.37 {ECO:0000256|ARBA:ARBA00011975};
GN OrderedLocusNames=MAE_04470 {ECO:0000313|EMBL:BAG00269.1};
OS Microcystis aeruginosa (strain NIES-843 / IAM M-2473).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Microcystaceae; Microcystis.
OX NCBI_TaxID=449447 {ECO:0000313|EMBL:BAG00269.1, ECO:0000313|Proteomes:UP000001510};
RN [1] {ECO:0000313|EMBL:BAG00269.1, ECO:0000313|Proteomes:UP000001510}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-843 {ECO:0000313|EMBL:BAG00269.1,
RC ECO:0000313|Proteomes:UP000001510};
RX PubMed=18192279; DOI=10.1093/dnares/dsm026;
RA Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M.,
RA Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A.,
RA Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M.,
RA Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M.;
RT "Complete genomic structure of the bloom-forming toxic cyanobacterium
RT Microcystis aeruginosa NIES-843.";
RL DNA Res. 14:247-256(2007).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016, ECO:0000256|RuleBase:RU000416}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP009552; BAG00269.1; -; Genomic_DNA.
DR RefSeq; WP_012264102.1; NC_010296.1.
DR AlphaFoldDB; B0JNA5; -.
DR STRING; 449447.MAE_04470; -.
DR REBASE; 17027; M.Mae843ORF4470P.
DR PaxDb; 449447-MAE_04470; -.
DR EnsemblBacteria; BAG00269; BAG00269; MAE_04470.
DR KEGG; mar:MAE_04470; -.
DR PATRIC; fig|449447.4.peg.422; -.
DR eggNOG; COG0270; Bacteria.
DR HOGENOM; CLU_006958_2_2_3; -.
DR BioCyc; MAER449447:MAE_RS02055-MONOMER; -.
DR Proteomes; UP000001510; Chromosome.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR CDD; cd00315; Cyt_C5_DNA_methylase; 1.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00675; dcm; 1.
DR PANTHER; PTHR10629; CYTOSINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10629:SF52; DNA (CYTOSINE-5)-METHYLTRANSFERASE 1; 1.
DR Pfam; PF00145; DNA_methylase; 1.
DR PRINTS; PR00105; C5METTRFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016}; Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT ACT_SITE 136
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 387 AA; 43230 MW; C6EFD2D29209ECD8 CRC64;
MDLQLSLFPD NQPSQAVSKQ KKAKLGRYER IQRELATVKR DPYQVLVDVN VPLQPLNSYN
FIDLFSGAGG ITQGLLQAGF NPVASAEISP IASATHQKNF PNCHHFCGDI HDFNTQEWLA
KIGNPFIHLV VGGPPCQGFS VAGKRDANDP RNHLFQEFIR LVSEIQPWYV VMENVPGILT
IKKGEIKQNI LEAFQSIGYG NISIAILESA AYGVPQIRPR AIFIANRFGL PNPYPSPQLV
PEKYQPIEAA ICDLPAYEPL PSINHEWTRH SPEYMARIAQ VPPGGSLYES YVDAFKRQYR
GKPSMTIKEN HGGTHIHPYL NRVISAREMA RLQTFPDSFI FEGTMKKAMW QIGNAVPPRL
AECIGYALIP YLNLIATGNK NIGEVAR
//
