ID B0JPW9_MICAN Unreviewed; 875 AA.
AC B0JPW9;
DT 18-MAR-2008, integrated into UniProtKB/TrEMBL.
DT 18-MAR-2008, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Probable chloride channel protein {ECO:0000313|EMBL:BAG03693.1};
GN OrderedLocusNames=MAE_38710 {ECO:0000313|EMBL:BAG03693.1};
OS Microcystis aeruginosa (strain NIES-843 / IAM M-2473).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Microcystaceae; Microcystis.
OX NCBI_TaxID=449447 {ECO:0000313|EMBL:BAG03693.1, ECO:0000313|Proteomes:UP000001510};
RN [1] {ECO:0000313|EMBL:BAG03693.1, ECO:0000313|Proteomes:UP000001510}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-843 {ECO:0000313|EMBL:BAG03693.1,
RC ECO:0000313|Proteomes:UP000001510};
RX PubMed=18192279; DOI=10.1093/dnares/dsm026;
RA Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M.,
RA Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A.,
RA Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M.,
RA Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M.;
RT "Complete genomic structure of the bloom-forming toxic cyanobacterium
RT Microcystis aeruginosa NIES-843.";
RL DNA Res. 14:247-256(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AP009552; BAG03693.1; -; Genomic_DNA.
DR RefSeq; WP_012266636.1; NC_010296.1.
DR AlphaFoldDB; B0JPW9; -.
DR STRING; 449447.MAE_38710; -.
DR PaxDb; 449447-MAE_38710; -.
DR EnsemblBacteria; BAG03693; BAG03693; MAE_38710.
DR KEGG; mar:MAE_38710; -.
DR PATRIC; fig|449447.4.peg.3505; -.
DR eggNOG; COG0038; Bacteria.
DR eggNOG; COG0517; Bacteria.
DR eggNOG; COG0589; Bacteria.
DR HOGENOM; CLU_016449_0_0_3; -.
DR BioCyc; MAER449447:MAE_RS16725-MONOMER; -.
DR Proteomes; UP000001510; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd01031; EriC; 1.
DR CDD; cd01988; Na_H_Antiporter_C; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR Gene3D; 3.40.50.620; HUPs; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45711; CHLORIDE CHANNEL PROTEIN; 1.
DR PANTHER; PTHR45711:SF10; CHLORIDE CHANNEL PROTEIN; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00582; Usp; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Chloride {ECO:0000256|ARBA:ARBA00023214};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 455..510
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 516..572
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 875 AA; 94332 MW; 4EDAB7A3EE467AF1 CRC64;
MGLFARHQNL RQWFKSQHFG RSATDSRYAL LVACLIGILS ALAAIILKLG IGWLGGWRVH
LVANSSPFLV LPLGGFLLGY SAGWIVEHFS PAAAGGGIPQ VKAALAKYPL PLSWRVALVK
MIGAILILGG GLTLGRRAPT VHIGAALAAQ LSVWLPTSPD HRRQMIAAGA AAGLAAGFTT
PIAGVLFVIE ELMRDVSSMT LETAIVASFT GAVVSMMLQN TPSIITEYAN ISFSAQEIPI
YCLLGVLAGL LGALFNQGIL FCSQLQRRWR LSLAWRIGLV SWLSGTVVAF LPDFFRDNTG
LREFLLAGEL SWQNTALAFV VYFFLTMISY SSGAPGGLLA PALVLGSCLG FLVGGIETKM
MGFGSEPSYT LAGMGAFFTG VVRVPVTAIV IVFELHRNFN IVLPLMLTCA VSYITAESIH
PGSLYQHLLS ASGIILNEET PSNDVLAHLS AMDVMQSQVE ILPADLPLGE VVKIMSRSHH
RGFPVVEQGR LLGIFTQSDL DKWRSKNSQT VLREIMTPNP ITVAPQAALT DVLFLLNRYQ
LSRLPVTDGQ KLVGIITRTD IIRVEADQLG GVCQLPQPST PSYVVYQTRS PAVGIGRILL
PIANPDTATA LFKIAAAIAS ERNYEIDCLY VITVPRLSSP AEVKVDTREG RKLLHRLERL
ARQQHISVHT QISVAQDIAD GILATIRERH SNLLIMGWTG EKSTTGAIFG FSVDTLIAEA
PCETILVKLG TKDCFPNDLN RERIWLIPTA GGPNAQRALA LLPSLLSLSE SSDHPELWLC
KIYSPTELLP DLSTLEVLQA SLQKAIAQPV VPLPIRSASP AEAVINLVES EDCSLVLLGA
SRESLLNQLL NGNIPSTIAR AVNCTVILVR GELSD
//
