ID   B0JWV7_MICAN            Unreviewed;       979 AA.
AC   B0JWV7;
DT   18-MAR-2008, integrated into UniProtKB/TrEMBL.
DT   18-MAR-2008, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   SubName: Full=Na-Ca exchanger/integrin-beta4 like {ECO:0000313|EMBL:BAG04844.1};
GN   OrderedLocusNames=MAE_50220 {ECO:0000313|EMBL:BAG04844.1};
OS   Microcystis aeruginosa (strain NIES-843 / IAM M-2473).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Microcystaceae; Microcystis.
OX   NCBI_TaxID=449447 {ECO:0000313|EMBL:BAG04844.1, ECO:0000313|Proteomes:UP000001510};
RN   [1] {ECO:0000313|EMBL:BAG04844.1, ECO:0000313|Proteomes:UP000001510}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-843 {ECO:0000313|EMBL:BAG04844.1,
RC   ECO:0000313|Proteomes:UP000001510};
RX   PubMed=18192279; DOI=10.1093/dnares/dsm026;
RA   Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M.,
RA   Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A.,
RA   Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M.,
RA   Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M.;
RT   "Complete genomic structure of the bloom-forming toxic cyanobacterium
RT   Microcystis aeruginosa NIES-843.";
RL   DNA Res. 14:247-256(2007).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP009552; BAG04844.1; -; Genomic_DNA.
DR   AlphaFoldDB; B0JWV7; -.
DR   STRING; 449447.MAE_50220; -.
DR   PaxDb; 449447-MAE_50220; -.
DR   EnsemblBacteria; BAG04844; BAG04844; MAE_50220.
DR   KEGG; mar:MAE_50220; -.
DR   eggNOG; COG2931; Bacteria.
DR   HOGENOM; CLU_325368_0_0_3; -.
DR   Proteomes; UP000001510; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.2030; -; 2.
DR   Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 2.
DR   InterPro; IPR038081; CalX-like_sf.
DR   InterPro; IPR003644; Calx_beta.
DR   InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR   InterPro; IPR001343; Hemolysn_Ca-bd.
DR   InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR   InterPro; IPR011121; Trp-rich_dom.
DR   PANTHER; PTHR11878:SF65; NA_CA-EXCHANGE PROTEIN, ISOFORM G; 1.
DR   PANTHER; PTHR11878; SODIUM/CALCIUM EXCHANGER; 1.
DR   Pfam; PF03160; Calx-beta; 3.
DR   Pfam; PF00353; HemolysinCabind; 3.
DR   Pfam; PF07483; W_rich_C; 2.
DR   PRINTS; PR00313; CABNDNGRPT.
DR   SMART; SM00237; Calx_beta; 3.
DR   SUPFAM; SSF51120; beta-Roll; 2.
DR   SUPFAM; SSF141072; CalX-like; 3.
DR   PROSITE; PS00330; HEMOLYSIN_CALCIUM; 3.
PE   4: Predicted;
KW   Integrin {ECO:0000313|EMBL:BAG04844.1};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          212..308
FT                   /note="Calx-beta"
FT                   /evidence="ECO:0000259|SMART:SM00237"
FT   DOMAIN          562..665
FT                   /note="Calx-beta"
FT                   /evidence="ECO:0000259|SMART:SM00237"
FT   DOMAIN          680..777
FT                   /note="Calx-beta"
FT                   /evidence="ECO:0000259|SMART:SM00237"
SQ   SEQUENCE   979 AA;  102769 MW;  0F3A4535FF9C8A48 CRC64;
     MTYDTVTGNG TVITGNKVDT LISIERCNLF GTEDNDFILG GWGSDSLLFS TSEGLRGNGG
     DDTIDGNSGE DLLFGEDGND FLIGGWGSDA LVGGDDNDRL IGVNPNASTP GQNEQDDLYG
     GAGADLFILG DANWSGYDDG STSSSGSGDY ADIQDANFSE GDRIQLRGSR ADYLVQQRPF
     SSDTVEIYLI KPLWEPDELI ARVRGYISLG DEVFVFVPAG PVTTITVAVS DASAGEPANA
     GVFTLTRSGN IGNALTVNYL LAGSASNGVD YSNLTGRVTF AAGSSTATVT INPLEDTAIE
     GNEVVLLQIA EGTGYTLGAT SGAVITLTDN DVYTAIEPAS LGSNITLVRD SANRLSARSS
     EETLPLYSLE DTPLQIGQYP DWQALAVERI DGLNQILWKN TRNNYLQVWY TDTNWRWLGG
     DSTNGLNTLD AYNLEKKFQF DANGDGRIGM TFTNLEAAGS VAIVRDTLNR LYARTSLGDT
     AIGAINGTPL TETSNPGRQI LGAETLNGIN QIVWRNTTTN ALELWTMDGD WQFAGNDAPI
     APTSPTALQL ELDFEMDLNG DTVIGRLPNL PDITLTVSPA TVTENGTPNL LYTFTRRGPL
     TNPLTVNFNV TGTATLTTDY TQTGALTFTA TGGTVRFNAG ASTAIITLDP VGDALIEPNE
     TVSLAITPGV DYTRGTTEAI TGTIANDDLP TLTIDNLIFL EGLEANALIP VRLNGPFGEP
     IRVNYTTANG TAIAVADYTA SSGILTIPAN TTTAFIRIPI ANDTLNEADE TFTVTLSNPV
     NATIARAMAT ITITDTLESD VSTVLTNGLE NLQLTGTNPI NGTGNAGNNR ITGNSGNNIL
     NGDLGNDTLA GNAGNDTLTG GAGIDQIEYR STRAFVASDF GVDTISDFVV NQDKIVLSKT
     TFAALTSGVG NGFNQPSNFA VVANNSLVAA SNAFIVYSSG TGHLFYNQNG SVAGLGTGAN
     FAVFTGNPSL TANDFLLVA
//