ID   B0K0B4_CAEBR            Unreviewed;       716 AA.
AC   B0K0B4;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=TBCC domain-containing protein 1 {ECO:0000256|ARBA:ARBA00017559};
GN   ORFNames=CBG22109 {ECO:0000313|EMBL:CAP38765.4,
GN   ECO:0000313|WormBase:CBG22109}, CBG_22109
GN   {ECO:0000313|EMBL:CAP38765.4};
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP38765.4, ECO:0000313|Proteomes:UP000008549};
RN   [1] {ECO:0000313|EMBL:CAP38765.4, ECO:0000313|Proteomes:UP000008549}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000313|EMBL:CAP38765.4,
RC   ECO:0000313|Proteomes:UP000008549};
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm,
CC       cytoskeleton, spindle pole {ECO:0000256|ARBA:ARBA00004647}.
CC   -!- SIMILARITY: Belongs to the TBCC family.
CC       {ECO:0000256|ARBA:ARBA00008848}.
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DR   EMBL; HE601428; CAP38765.4; -; Genomic_DNA.
DR   AlphaFoldDB; B0K0B4; -.
DR   STRING; 6238.B0K0B4; -.
DR   WormBase; CBG22109; CBP48480; WBGene00040735; -.
DR   eggNOG; KOG4416; Eukaryota.
DR   InParanoid; B0K0B4; -.
DR   OMA; QDPFQID; -.
DR   OrthoDB; 2879044at2759; -.
DR   Proteomes; UP000008549; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0031616; C:spindle pole centrosome; IBA:GO_Central.
DR   GO; GO:0051661; P:maintenance of centrosome location; IBA:GO_Central.
DR   GO; GO:0051684; P:maintenance of Golgi location; IBA:GO_Central.
DR   Gene3D; 2.160.20.70; -; 1.
DR   InterPro; IPR017901; C-CAP_CF_C-like.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR006599; CARP_motif.
DR   InterPro; IPR039589; TBCC1.
DR   InterPro; IPR012945; Tubulin-bd_cofactor_C_dom.
DR   PANTHER; PTHR16052:SF0; TBCC DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR16052; UNCHARACTERIZED; 1.
DR   Pfam; PF07986; TBCC; 1.
DR   SMART; SM00673; CARP; 2.
DR   PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008549}.
FT   DOMAIN          479..623
FT                   /note="C-CAP/cofactor C-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51329"
FT   REGION          65..192
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        138..152
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        171..185
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   716 AA;  83208 MW;  EE670D549A5B34E7 CRC64;
     MWNSVVRVKF GQRLENANNR SRRDKPRVPK EEIDDAVLHY VPGTKPVEQN HVQNHVQSQS
     IEQKIILPPP NPNHHHHRYS SPPHQNRRRT SSEATHQTPS RKLLPAQPPS EYRRHLKFPQ
     RPHHNHHRGP RTYYSDDDDG DSEGEDDDDD LPTPPPPIFA TRLTSDSWEN QRLRPGRRQL
     PETPDLPKHG ELPQLFSISH TNNLSHFLQF FLLQNNNRTP SPFLLYALSS PWRPQLTEQQ
     KEEKEEKEFQ QKIVMTNIYV WVRTSRSLQF FYPTVDVEKD DPFSVYYEIA MDVIGLMKEC
     DRISSEEFET MGKGRISKVY TEAIFQNAVE HGNINARLKL LVFSLLFAAI QQRTPDMAKS
     NRNDIVLTRI SKYFGPIFKL LFQMDVGKRL QDRDIVQAIG SGQGYKFLDV LFEGTIKHKH
     GNSNHHGVRP LSLIVPLILD KVNSISLPFL CNEIRRHLIK DPYHIDEFAS EKSPQIFSTV
     RRTTLAHNSR RVVHLHYINR IEVLRKDEFA NVHLRICNDK PKASFVFVPL RCETVFLDSL
     FYTQWILLGA VRGIVIVKNC QNTRISVSCE QLIILDSKNL EIHFMSPKKP LISSSVGITL
     APFNTIYEGQ EEFLEENGHY FNNNLVFKEP IMFSSGSWTM DTSKFVCQST PLDAMDQQFE
     TLLNSLPEEY RIAHYRNTIE AQKMMAAEPE KCRVSDVATN FDLLYLKSKI EKKEEE
//