ID   B0PF61_9FIRM            Unreviewed;       915 AA.
AC   B0PF61;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=N-acetylmuramoyl-L-alanine amidase {ECO:0000313|EMBL:EDS09994.1};
DE            EC=3.5.1.28 {ECO:0000313|EMBL:EDS09994.1};
GN   ORFNames=ANACOL_03440 {ECO:0000313|EMBL:EDS09994.1};
OS   Anaerotruncus colihominis DSM 17241.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Anaerotruncus.
OX   NCBI_TaxID=445972 {ECO:0000313|EMBL:EDS09994.1, ECO:0000313|Proteomes:UP000003803};
RN   [1] {ECO:0000313|EMBL:EDS09994.1, ECO:0000313|Proteomes:UP000003803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17241 {ECO:0000313|EMBL:EDS09994.1,
RC   ECO:0000313|Proteomes:UP000003803};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Anaerotruncus colihominis(DSM 17241).";
RL   Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EDS09994.1, ECO:0000313|Proteomes:UP000003803}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17241 {ECO:0000313|EMBL:EDS09994.1,
RC   ECO:0000313|Proteomes:UP000003803};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDS09994.1}.
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DR   EMBL; ABGD02000025; EDS09994.1; -; Genomic_DNA.
DR   RefSeq; WP_006876302.1; NZ_DS544186.1.
DR   AlphaFoldDB; B0PF61; -.
DR   STRING; 169435.ERS852551_00369; -.
DR   eggNOG; COG0860; Bacteria.
DR   eggNOG; COG1649; Bacteria.
DR   HOGENOM; CLU_313244_0_0_9; -.
DR   Proteomes; UP000003803; Unassembled WGS sequence.
DR   GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR   CDD; cd02696; MurNAc-LAA; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 1.
DR   InterPro; IPR003790; GHL10.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR002508; MurNAc-LAA_cat.
DR   PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR   PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR   Pfam; PF01520; Amidase_3; 1.
DR   Pfam; PF02638; GHL10; 1.
DR   SMART; SM00646; Ami_3; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EDS09994.1}.
FT   DOMAIN          798..910
FT                   /note="MurNAc-LAA"
FT                   /evidence="ECO:0000259|SMART:SM00646"
SQ   SEQUENCE   915 AA;  97011 MW;  C05873B622E23D8C CRC64;
     MKHETKRTIL RTLLASLAIV AATCAVLYAS DLLTSPISSK TPPAGIPAAG EQLHALIVRT
     RGNADFPSAP GLSAKQQRAQ LDEIAAFAGE YGYNAVFFEA VPSCDALYRS SILPSSAYWM
     GEQGAFAFFD PLDYLVNVCK ESGIQVYAMI DPFAVSAEDL AESSPASKNP EWIAADGRFN
     PTELGVQQLA GSVAAELATR YDIAGIVLEG VEPAGFAAVD NYMAALSETA AQVRSALRLK
     EGQRLGMLLP SSASPSAAAL AESGALDFAV PDLAGLTEQE LPSVLAVWQT SGVPYYPLYI
     ASDDTAFTHL ADAILYQERT SGSGLVVSSF SALHTDSRAA AYSLAASFAQ TEQANMPDLT
     YSTEFAVTRP TETLTVGSDW ESYFITGTSD PSLPVFYNGA EIARSPSGLW GVLVNVPYGT
     NTYTFTQGGV NKTATIVRNQ PSASAAISAI VKSSVYPSNA EAVLPGQSLK LSCTAPGGGT
     VTASVGGLAA TLEPVAQAAD GVAVTYQATI DVSSLAQDGE VKNIGPVTYT LEYGGVNSEQ
     QSAGDVYACG NGARPVAVMK TFIVPVNANA ADDGEYATIL KEDCVDYITE NAGGYYHLSS
     GGYVLKGAVD ILEGSQTAET NASSLSLEQT DKGEKLTIRG TARPAFDGAM DDDSVTIRLY
     NVTGFENLST AALESKLCSS IESSTEQNTV TLTFHLNEGV RLLGWDVRFN DNDTVIYLKQ
     RPTLDRASAK PLSGITVVLD PGHGGDDPGA AGVPGQNGPF ENILNLADSY AIESRLTALG
     AKVHVLHNNE NMTLNERVEL AEQFDADMFI SSHHNSLSET VDSNEVSGIE VYYYNDQSEL
     LAEKIGWSLA EDTGRKLRFT EQSWYRVTMM TGCPAVLVES GYICNPTEYE EIADEYAMFK
     YGNAVADAVL QYFAA
//