ID   B0RC00_CLAMS            Unreviewed;      1006 AA.
AC   B0RC00;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 102.
DE   SubName: Full=Glutamate-ammonia-ligase adenylyltransferase {ECO:0000313|EMBL:CAQ01728.1};
DE            EC=2.7.7.42 {ECO:0000313|EMBL:CAQ01728.1};
GN   Name=glnE {ECO:0000313|EMBL:CAQ01728.1};
GN   OrderedLocusNames=CMS1618 {ECO:0000313|EMBL:CAQ01728.1};
OS   Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / DSM 20744
OS   / JCM 9667 / LMG 2889 / C-1) (Corynebacterium sepedonicum).
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Clavibacter.
OX   NCBI_TaxID=31964 {ECO:0000313|EMBL:CAQ01728.1, ECO:0000313|Proteomes:UP000001318};
RN   [1] {ECO:0000313|EMBL:CAQ01728.1, ECO:0000313|Proteomes:UP000001318}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1
RC   {ECO:0000313|Proteomes:UP000001318};
RX   PubMed=18192393; DOI=10.1128/JB.01598-07;
RA   Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J.,
RA   Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D.,
RA   Parkhill J., Ishimaru C.A.;
RT   "Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp.
RT   sepedonicus suggests recent niche adaptation.";
RL   J. Bacteriol. 190:2150-2160(2008).
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DR   EMBL; AM849034; CAQ01728.1; -; Genomic_DNA.
DR   RefSeq; WP_012298984.1; NZ_MZMN01000003.1.
DR   AlphaFoldDB; B0RC00; -.
DR   STRING; 31964.CMS1618; -.
DR   KEGG; cms:CMS1618; -.
DR   eggNOG; COG1391; Bacteria.
DR   HOGENOM; CLU_006233_1_0_11; -.
DR   OrthoDB; 9759366at2; -.
DR   Proteomes; UP000001318; Chromosome.
DR   GO; GO:0008882; F:[glutamate-ammonia-ligase] adenylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   CDD; cd05401; NT_GlnE_GlnD_like; 2.
DR   Gene3D; 1.20.120.1510; -; 1.
DR   Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 2.
DR   Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 2.
DR   InterPro; IPR023057; GlnE.
DR   InterPro; IPR005190; GlnE_rpt_dom.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR013546; PII_UdlTrfase/GS_AdlTrfase.
DR   PANTHER; PTHR30621:SF0; BIFUNCTIONAL GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE_ADENYLYL-REMOVING ENZYME; 1.
DR   PANTHER; PTHR30621; GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE; 1.
DR   Pfam; PF08335; GlnD_UR_UTase; 2.
DR   Pfam; PF03710; GlnE; 2.
DR   SUPFAM; SSF81301; Nucleotidyltransferase; 2.
DR   SUPFAM; SSF81593; Nucleotidyltransferase substrate binding subunit/domain; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW   ECO:0000313|EMBL:CAQ01728.1}; Transferase {ECO:0000313|EMBL:CAQ01728.1}.
FT   DOMAIN          80..336
FT                   /note="Glutamate-ammonia ligase adenylyltransferase
FT                   repeated"
FT                   /evidence="ECO:0000259|Pfam:PF03710"
FT   DOMAIN          358..497
FT                   /note="PII-uridylyltransferase/Glutamine-synthetase
FT                   adenylyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF08335"
FT   DOMAIN          602..829
FT                   /note="Glutamate-ammonia ligase adenylyltransferase
FT                   repeated"
FT                   /evidence="ECO:0000259|Pfam:PF03710"
FT   DOMAIN          867..994
FT                   /note="PII-uridylyltransferase/Glutamine-synthetase
FT                   adenylyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF08335"
SQ   SEQUENCE   1006 AA;  109946 MW;  D6A0384B47BA799B CRC64;
     MRRGQTLLGA LARAGFARLS EVGEALEEAA ELSGWAEAEL VEALHSSADP DGALDALVRL
     LREDPERTRA VLADADARHR LARVLGSSRG LGEFLTRHTD ELDAFARPLE ATPAPADVRD
     RMLDAVRAVD GVAGLTGPSA RSALRVRYRA LVARVAAWDL VHPDPLAAVR PVTAALADLA
     GAALEASLSV ARAELSAAGT FGRARPDEIA ATRLAIIGMG KAGARELNYV SDVDVIFVAE
     AATDAEGEPV IEPARAVELA TRLAVLAMRG IDEHEIEPAL WEVDANLRPE GKAGALVRTL
     DSHLAYYERW AKDWEFQALL KARPLAGDAE LGGRFADAVA PLVWSSASRE GFVGQVQRMR
     TRVTDNIPAD QLHQQIKLGP GGIRDIEFTV QLLQLVHGQG DEAVRDCSTL AALVALADAG
     YIGRTEAGEF AKDYRYLRLL EHRLQLDQLR RTHLMPTEEE RLRILARSTG LDGRAEELTA
     RWTATKTAVR TLHERLFYRP LLAAVASLPE ESLALTSDQA AARLSAIGFV DARGALAHIR
     ALTQGVSRSS AIQRHLLPVL LQWFADGPDP DHGLLAFRRL SEALGQSNWF LRMLRDSAGA
     AQRLAQVLSG SRFVSELLDR VPETAAWLAR DEDLRPRTWA ALEEEAVATV NRHPTADAAA
     AALRTLRRRE VLRLAIGAIV GVTHVETLGP SLADITTATL RGVMRAIRRE DGPWPEFAVV
     AMGRYGGAEL GFGSDADVMY VFRPIAGMDP ELAQRRAQLI VSELTRLTED SRLPLDLDTG
     LRPEGRNGPV VRSFASYRAY YERWSLTWEA QALLRARGVV GDSGLIADFT SLADRFRYPD
     GIGDADVREI KRIKARVENE RLPQGADPTR HLKLGRGSLS DVEWLVQLIQ LQHAHEHPAL
     RTPTTLGALE AAVASHLVTE DDAARLRDAW LLASRVRSAM TLWTNRTADV LPADRAALDA
     IARLLEYPPG SACVLEEEYL GVTRRSRAVF ERLFYGIDDR PDPRSV
//