ID B0S637_DANRE Unreviewed; 422 AA.
AC B0S637; A0A8N7T809;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 2.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=GTPase IMAP family member 7-like {ECO:0000313|RefSeq:XP_693796.5};
DE SubName: Full=Si:dkeyp-67a8.4 {ECO:0000313|Ensembl:ENSDARP00000113487};
GN Name=si:dkeyp-67a8.4 {ECO:0000313|Ensembl:ENSDARP00000113487,
GN ECO:0000313|ZFIN:ZDB-GENE-070912-666};
GN Synonyms=LOC565424 {ECO:0000313|RefSeq:XP_693796.5};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000113487};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000113487, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000113487};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2] {ECO:0000313|Ensembl:ENSDARP00000113487}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000113487};
RG Ensembl;
RL Submitted (MAY-2013) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_693796.5}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_693796.5};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
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DR EMBL; BX323566; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_693796.5; XM_688704.8.
DR Ensembl; ENSDART00000142709; ENSDARP00000113487; ENSDARG00000092823.
DR Ensembl; ENSDART00000142709.3; ENSDARP00000113487.2; ENSDARG00000092823.3.
DR GeneID; 565424; -.
DR KEGG; dre:565424; -.
DR AGR; ZFIN:ZDB-GENE-070912-666; -.
DR ZFIN; ZDB-GENE-070912-666; si:dkeyp-67a8.4.
DR eggNOG; ENOG502R7PE; Eukaryota.
DR HOGENOM; CLU_010468_3_0_1; -.
DR OMA; MDNKYWN; -.
DR OrthoDB; 4265569at2759; -.
DR TreeFam; TF330845; -.
DR Proteomes; UP000000437; Chromosome 7.
DR Bgee; ENSDARG00000092823; Expressed in gastrula and 8 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01852; AIG1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903:SF186; GTPASE IMAP FAMILY MEMBER 4-LIKE-RELATED; 1.
DR PANTHER; PTHR10903; GTPASE, IMAP FAMILY MEMBER-RELATED; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 246..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..214
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
SQ SEQUENCE 422 AA; 43746 MW; 10382561E4B525E4 CRC64;
MGASESLQEK RIVLLGKTGD GKSSAGNTIL KQEVFKSKAS PESVTVECVS GDRKIDGKKI
TVIDTPGLFD TAVDEETIKS EIIRSVIESS PGPDVFTIVL KVGRYTGHEM EIVDKIVEYC
GEDTFNHSVV LFTHGEQLEG QTIEEFVKMS PKLQELVNKC GGRCHVIDSK YWKKRQMGYR
SNRVQVKKLL ETIEEKLKDN KNSCYTNELL QMVEEEIQEE VKNMDEVSLS PEEKREIAKK
IVHKKLLIRL AGVATGTLTG AFLGIGVAVA SVVTLLKAVG TIAGAAAAGA SGLAGGASGL
AAGASGLVTG ASGLAAGASG LAAGTVAVEA GLVTGASAGI GAGLGAAAGS GITAGIVVGA
AALAGAIGGG ITGCKAADES DSVCDAIKNA AKINYENAKG VVKKAQKHQH KLLKIKKNDK
LE
//
