ID B0SJC8_LEPBP Unreviewed; 332 AA.
AC B0SJC8;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Putative tyrosine specific protein phosphatase {ECO:0000313|EMBL:ABZ96691.1};
DE EC=3.1.3.48 {ECO:0000313|EMBL:ABZ96691.1};
GN OrderedLocusNames=LEPBI_I0553 {ECO:0000313|EMBL:ABZ96691.1};
OS Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris).
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=456481 {ECO:0000313|EMBL:ABZ96691.1, ECO:0000313|Proteomes:UP000001847};
RN [1] {ECO:0000313|EMBL:ABZ96691.1, ECO:0000313|Proteomes:UP000001847}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Patoc 1 / ATCC 23582 / Paris
RC {ECO:0000313|Proteomes:UP000001847};
RX PubMed=18270594; DOI=10.1371/journal.pone.0001607;
RA Picardeau M., Bulach D.M., Bouchier C., Zuerner R.L., Zidane N.,
RA Wilson P.J., Creno S., Kuczek E.S., Bommezzadri S., Davis J.C., McGrath A.,
RA Johnson M.J., Boursaux-Eude C., Seemann T., Rouy Z., Coppel R.L.,
RA Rood J.I., Lajus A., Davies J.K., Medigue C., Adler B.;
RT "Genome sequence of the saprophyte Leptospira biflexa provides insights
RT into the evolution of Leptospira and the pathogenesis of leptospirosis.";
RL PLoS ONE 3:E1607-E1607(2008).
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DR EMBL; CP000786; ABZ96691.1; -; Genomic_DNA.
DR RefSeq; WP_012387578.1; NC_010602.1.
DR AlphaFoldDB; B0SJC8; -.
DR STRING; 456481.LEPBI_I0553; -.
DR KEGG; lbi:LEPBI_I0553; -.
DR HOGENOM; CLU_836238_0_0_12; -.
DR OrthoDB; 9806482at2; -.
DR BioCyc; LBIF456481:LEPBI_RS02715-MONOMER; -.
DR Proteomes; UP000001847; Chromosome I.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR045544; TCAD9.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR46377; DUAL SPECIFICITY PROTEIN PHOSPHATASE 19; 1.
DR PANTHER; PTHR46377:SF6; MAP KINASE PHOSPHATASE 4; 1.
DR Pfam; PF00782; DSPc; 1.
DR Pfam; PF19974; TCAD9; 1.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00195; DSPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ABZ96691.1};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Prenylation {ECO:0000256|ARBA:ARBA00023289};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000001847}.
FT DOMAIN 179..332
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 255..320
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 332 AA; 38610 MW; 8BA2CEC2231EEA8E CRC64;
MHGDLNGANI IIDAQDNVWM IDFFHTHRGH IIRDLLKLEN DVLYIFCKIE SEAEWKEAIV
LTEILHNQED LGIPIPFDPP QALQNDKLKK AYRVIAKLRS YYPRLVKLDR DPYQMHVGAL
RYAMHSLSFD ECNDWQKKWA LYAGSKLIDK IKTYIQKSKV LRIDYLKPIQ DGMDFPFTNI
GLTILPGRKD RGRVLFDDLK TIKKEGISHI LSLITEQEYT QYGVLDLKTE IPQFGLEQKQ
VSILDQRVPS FTQMKEIVEW MDLILSKNQK LLIHCVGGLG RSGTVACAYL IWKAKLDAKS
AIQKVRESRS ERAVESHEQI RFLELWEKTV QN
//
