ID B0T837_CAUSK Unreviewed; 584 AA.
AC B0T837;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:ABZ72800.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:ABZ72800.1};
GN OrderedLocusNames=Caul_3673 {ECO:0000313|EMBL:ABZ72800.1};
OS Caulobacter sp. (strain K31).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=366602 {ECO:0000313|EMBL:ABZ72800.1};
RN [1] {ECO:0000313|EMBL:ABZ72800.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K31 {ECO:0000313|EMBL:ABZ72800.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Bruce D., Goodwin L., Thompson L.S., Brettin T.,
RA Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Kim E., Stephens C., Richardson P.;
RT "Complete sequence of chromosome of Caulobacter sp. K31.";
RL Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000927; ABZ72800.1; -; Genomic_DNA.
DR AlphaFoldDB; B0T837; -.
DR STRING; 366602.Caul_3673; -.
DR KEGG; cak:Caul_3673; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_2_5; -.
DR OrthoDB; 9789078at2; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000313|EMBL:ABZ72800.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:ABZ72800.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 83..192
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 251..535
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 584 AA; 62431 MW; 53495422BFC18B1C CRC64;
MSLANLAPGG APRAWRWLIE RVWRLEHAFE RSRAAARPQD DTRIRIFFVM AIFGVAFTVL
ALGATWAAVF SKVGGNGYLA STEGARGDLV DRNGQLLAVD LTHYALYIDP KDVWDAKATR
LALGKALPEV PAKRLDQAVF SDRRSFVVGG MTPAEKQAIF DLGLPGVQFE EQARRVYPLG
ASAAHFIGFV DKGGRGLSGA EKALDKPVRD AAAKGPDGAI PLSIDLRIQA ALEDEVRKTA
IEFQAKDAVG IVTNVHTGEI LGMVSYPDYD PNRLDQASSE QMTNHAAASV YEMGSTFKAF
TVAIGLDTGA ATPASTFDAR EPFKLGYRTI HDFHAARKIL TLVEVFQHSS NIGTAMLAER
IGGERLSHYF AALGLTKPAK VELLESARPL TPKKWDDDSV ASTSFGHGIN VSPLALAQAM
GALLNGGTLQ PLTIRKMAPG VRPEGPRAVS EETSQQMLQI MRANVTGGSG KSANIPGLTV
GGKTGTGEKY DPAIRGYNHQ RQVSSFAAVF PTEGAIEADR YFVLVLLDEP KGNAKTSGFS
TGGWVAAPAA GRVIDRIAPF LGVRRQADIF TVAQQPQAAP EAGL
//
