ID B0TEB0_HELMI Unreviewed; 576 AA.
AC B0TEB0;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Pas sensor diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:ABZ85592.1};
GN ORFNames=HM1_3091 {ECO:0000313|EMBL:ABZ85592.1};
OS Heliobacterium modesticaldum (strain ATCC 51547 / Ice1).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Heliobacteriaceae;
OC Heliomicrobium.
OX NCBI_TaxID=498761 {ECO:0000313|EMBL:ABZ85592.1, ECO:0000313|Proteomes:UP000008550};
RN [1] {ECO:0000313|EMBL:ABZ85592.1, ECO:0000313|Proteomes:UP000008550}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51547 / Ice1 {ECO:0000313|Proteomes:UP000008550};
RX PubMed=18441057; DOI=10.1128/JB.00299-08;
RA Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M.,
RA Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E.,
RA Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T.,
RA Raymond J., Chen M., Blankenship R.E., Touchman J.W.;
RT "The genome of Heliobacterium modesticaldum, a phototrophic representative
RT of the Firmicutes containing the simplest photosynthetic apparatus.";
RL J. Bacteriol. 190:4687-4696(2008).
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DR EMBL; CP000930; ABZ85592.1; -; Genomic_DNA.
DR AlphaFoldDB; B0TEB0; -.
DR STRING; 498761.HM1_3091; -.
DR KEGG; hmo:HM1_3091; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_50_9; -.
DR Proteomes; UP000008550; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000008550}.
FT DOMAIN 90..142
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 173..307
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 318..567
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT REGION 555..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 576 AA; 64514 MW; B7D36CB8861F9BEF CRC64;
MIEGKVNKGS SHLVQFAEEE LRAIQESTFD AIFTCSLDGV LTGIWPGAAR RNSHLDGLLG
CSLNDVVHPE DLETVKAFIS KVKRLGTVRP GPECRLRQLD GSWRWYSVNA SLVCGVDGEP
LYVAGVARDL SEQKETEKHL KHLATHDYLT GIPNRYYFDG ALSRARRLAK EGTVSSLLLI
DVDKFNLVND LLDHDMGDRL LTNLSRLLKS QIRRDDVLAR LSGDEFGLLL HGMAEAEAEK
VALNLCHIVK ERDLCPVLEG CDLRFTVSIG VAEINGHQDV RQVLSRAGAA LHMAKMAGRS
QVVVAYANER MFSRLEETSR LIQIVRGADR EGRFQLFFMP VVRSSDGAVE HYEALLRLRD
GDGKLIPPAT FIPVAESFGL MGDIERWVVA EAVRFLVKNP QLRLYVNLSG ESLGDKEILN
FIEEIVQTTP AIHGRLGFEI TETAAVRDLM SAEQWVQKLR SLGCRFALDD FGSGYSSFAY
LNKLPVDFIK IDGSFVRSID HDPERHALVK GINQLVHSLG KRTISEYVEN DRIWRLIREM
GIEYGQGYYL GEPSPLPQDM ASESTELDPR QGIKRR
//
