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Database: UniProt
Entry: B0UUZ9
LinkDB: B0UUZ9
Original site: B0UUZ9 
ID   RHLB_HISS2              Reviewed;         419 AA.
AC   B0UUZ9;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   16-OCT-2019, entry version 76.
DE   RecName: Full=ATP-dependent RNA helicase RhlB {ECO:0000255|HAMAP-Rule:MF_00661};
DE            EC=3.6.4.13 {ECO:0000255|HAMAP-Rule:MF_00661};
GN   Name=rhlB {ECO:0000255|HAMAP-Rule:MF_00661};
GN   OrderedLocusNames=HSM_0041;
OS   Histophilus somni (strain 2336) (Haemophilus somnus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Histophilus.
OX   NCBI_TaxID=228400;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2336;
RG   US DOE Joint Genome Institute;
RA   Siddaramappa S., Duncan A.J., Challacombe J.F., Rainey D.,
RA   Gillaspy A.F., Carson M., Gipson J., Gipson M., Bruce D., Detter J.C.,
RA   Han C.S., Land M., Tapia R., Thompson L.S., Orvis J., Zaitshik J.,
RA   Barnes G., Brettin T.S., Dyer D.W., Inzana T.J.;
RT   "Complete sequence of Haemophilus somnus 2336.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DEAD-box RNA helicase involved in RNA degradation. Has
CC       RNA-dependent ATPase activity and unwinds double-stranded RNA.
CC       {ECO:0000255|HAMAP-Rule:MF_00661}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00661};
CC   -!- SUBUNIT: Component of the RNA degradosome, which is a multiprotein
CC       complex involved in RNA processing and mRNA degradation.
CC       {ECO:0000255|HAMAP-Rule:MF_00661}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00661}.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. RhlB
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00661}.
DR   EMBL; CP000947; ACA32052.1; -; Genomic_DNA.
DR   RefSeq; WP_012341256.1; NC_010519.1.
DR   SMR; B0UUZ9; -.
DR   EnsemblBacteria; ACA32052; ACA32052; HSM_0041.
DR   GeneID; 31486316; -.
DR   KEGG; hsm:HSM_0041; -.
DR   HOGENOM; HOG000268807; -.
DR   KO; K03732; -.
DR   OMA; TRFHDFK; -.
DR   OrthoDB; 626183at2; -.
DR   BioCyc; HSOM228400:G1GB8-41-MONOMER; -.
DR   Proteomes; UP000008543; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00661; DEAD_helicase_RhlB; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR023554; RNA_helicase_ATP-dep_RhlB.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Helicase; Hydrolase;
KW   Nucleotide-binding; Reference proteome; RNA-binding.
FT   CHAIN         1    419       ATP-dependent RNA helicase RhlB.
FT                                /FTId=PRO_1000082848.
FT   DOMAIN       40    217       Helicase ATP-binding. {ECO:0000255|HAMAP-
FT                                Rule:MF_00661}.
FT   DOMAIN      241    388       Helicase C-terminal. {ECO:0000255|HAMAP-
FT                                Rule:MF_00661}.
FT   NP_BIND      53     60       ATP. {ECO:0000255|HAMAP-Rule:MF_00661}.
FT   MOTIF         9     37       Q motif.
FT   MOTIF       163    166       DEAD box.
SQ   SEQUENCE   419 AA;  47485 MW;  D034599A55B55D23 CRC64;
     MQNSHLSQQR FSDLALHRIV QQAIKEKGFE FCTPIQALSL PITLKGQDIA GQAQTGTGKT
     IAFLTATFHH LLQKNNINSS EQPRALILAP TRELVVQIAN DANFLVQATG LKTGLAYGGE
     GYDKQLKVID RGIDILIGTT GRVIDYVKQG IIRLDYIQVV VLDEADRMFD LGFIRDIRYL
     LRKCPVPQQR LTMLFSATLS YKVRELAFEH MNDPQYVEIE PLQKTGHRIR EELFYPSNQD
     KMALLMTLLE EEWPERCIIF SNTKHRCEEI WGYLSADGHR VGLLTGDVMQ KKRLSLLKQF
     TDGTLDVLVA TDVAARGLHI PDVTHVFNYD LPDDCEDYVH RIGRTGRAGE SGISISFACE
     EYAINLPAIE EYIGHSIPVS QYDAKALIED LPTPHRIKRG AFDSRSNLQR TVKRLKKTY
//
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