ID B0VXF8_CALJA Unreviewed; 441 AA.
AC B0VXF8;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Protein FAM176C {ECO:0000313|EMBL:JAB30898.1};
GN Name=C21ORF63 {ECO:0000313|EMBL:ABZ80242.1};
GN Synonyms=EVA1C {ECO:0000313|EMBL:JAB30898.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:ABZ80242.1};
RN [1] {ECO:0000313|EMBL:ABZ80242.1}
RP NUCLEOTIDE SEQUENCE.
RA Antonellis A., Benjamin B., Blakesley R.W., Bouffard G.G., Brinkley C.,
RA Brooks S., Chu G., Chub I., Coleman H., Fuksenko T., Gestole M.,
RA Gregory M., Guan X., Gupta J., Gurson N., Han E., Han J., Hansen N.,
RA Hargrove A., Hines-Harris K., Ho S.-L., Hu P., Hunter G., Hurle B.,
RA Idol J.R., Johnson T., Knight E., Kwong P., Lee-Lin S.-Q., Legaspi R.,
RA Madden M., Maduro Q.L., Maduro V.B., Margulies E.H., Masiello C.,
RA Maskeri B., McDowell J., Merkulov G., Montemayor C., Mullikin J.C.,
RA Park M., Prasad A., Ramsahoye C., Reddix-Dugue N., Riebow N., Schandler K.,
RA Schueler M.G., Sison C., Smith L., Stantripop S., Thomas J.W., Thomas P.J.,
RA Tsipouri V., Young A., Green E.D.;
RT "NISC Comparative Sequencing Initiative.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB30898.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Cerebellum {ECO:0000313|EMBL:JAB43813.1}, and Cerebral cortex
RC {ECO:0000313|EMBL:JAB30898.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
CC -!- SIMILARITY: Belongs to the EVA1 family.
CC {ECO:0000256|ARBA:ARBA00006023}.
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DR EMBL; DP000592; ABZ80242.1; -; Genomic_DNA.
DR EMBL; GAMR01003034; JAB30898.1; -; mRNA.
DR EMBL; GAMP01008942; JAB43813.1; -; mRNA.
DR RefSeq; XP_002761414.2; XM_002761368.4.
DR AlphaFoldDB; B0VXF8; -.
DR GeneID; 100394577; -.
DR KEGG; cjc:100394577; -.
DR CTD; 59271; -.
DR eggNOG; KOG4729; Eukaryota.
DR HOGENOM; CLU_050537_0_1_1; -.
DR OrthoDB; 56324at2759; -.
DR TreeFam; TF328177; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR CDD; cd22828; Gal_Rha_Lectin_EVA1_EVA1C_rpt1; 1.
DR CDD; cd22829; Gal_Rha_Lectin_EVA1_EVA1C_rpt2; 1.
DR Gene3D; 2.60.120.740; -; 2.
DR InterPro; IPR039500; EVA1_dom.
DR InterPro; IPR000922; Lectin_gal-bd_dom.
DR InterPro; IPR043159; Lectin_gal-bd_sf.
DR PANTHER; PTHR46780; PROTEIN EVA-1; 1.
DR PANTHER; PTHR46780:SF4; PROTEIN EVA-1 HOMOLOG C; 1.
DR Pfam; PF14851; FAM176; 1.
DR Pfam; PF02140; Gal_Lectin; 2.
DR PROSITE; PS50228; SUEL_LECTIN; 2.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 322..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..159
FT /note="SUEL-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50228"
FT DOMAIN 168..260
FT /note="SUEL-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50228"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 358..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..385
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 441 AA; 49429 MW; 67590A155827E2A6 CRC64;
MLLPGPARPP PAPQPAQHPG LRRQVEPPGQ LLRLFYCTVL VCSKEISALT DFSGYLTKLL
QNHTAYACDG DYLNLQCPRH STISVQSAFY GQDYQMCSSQ KPASQREDSL TCVAPTTFQK
VLDECQNQRA CHLLVNSRVF GPDLCPGSSK YLLVSFKCQP NELKNKTVCE DQELKLHCHE
SKFLNIYSAT YGRRTQERDL CSSKAEWLPP FDCLSYSALQ VLSRRCYGKQ RCKIVVNNHH
FGSPCLPGVK KYLTVTYACV PKNILTAIDP GIANLKPSLK QKDGEYDINF DPSGSRVLRK
DGILVSNSLA AFAYIRAHPE RAALLFVSSV CIGLALTLCA LVIRESCTKD VREMQLGREQ
LVPGSDRAEE DSEDEEEEED SSDSDFPGEL SGFHRTSYPV YSSIEAAELA ERIERREQII
QEIWMNSGLD TSLPRNMGQF Y
//
