ID B0VZJ6_CULQU Unreviewed; 1439 AA.
AC B0VZJ6;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE RecName: Full=Tonsoku-like protein {ECO:0008006|Google:ProtNLM};
GN Name=6031028 {ECO:0000313|EnsemblMetazoa:CPIJ000307-PA};
GN ORFNames=CpipJ_CPIJ000307 {ECO:0000313|EMBL:EDS31733.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS31733.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS31733.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ000307-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ000307-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
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DR EMBL; DS231814; EDS31733.1; -; Genomic_DNA.
DR RefSeq; XP_001841880.1; XM_001841828.1.
DR STRING; 7176.B0VZJ6; -.
DR EnsemblMetazoa; CPIJ000307-RA; CPIJ000307-PA; CPIJ000307.
DR GeneID; 6031028; -.
DR KEGG; cqu:CpipJ_CPIJ000307; -.
DR VEuPathDB; VectorBase:CPIJ000307; -.
DR VEuPathDB; VectorBase:CQUJHB013994; -.
DR eggNOG; KOG0504; Eukaryota.
DR HOGENOM; CLU_002128_0_0_1; -.
DR InParanoid; B0VZJ6; -.
DR OMA; AHINDKG; -.
DR OrthoDB; 2663363at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR46358; TONSOKU-LIKE PROTEIN; 1.
DR PANTHER; PTHR46358:SF1; TONSOKU-LIKE PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF17874; TPR_MalT; 1.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 166..199
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 543..575
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 576..608
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 612..644
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 508..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 697..779
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 791..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 836..917
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 954..979
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..743
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 836..852
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 853..878
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..917
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 956..974
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1439 AA; 161861 MW; 5069AE8A341BE2F3 CRC64;
MSSETDVEEQ RLLRRKKKAS EAGNLLLLAE ACRKLGEMYH EQSEHRKALI EYKLVAKAFQ
NLKMQMELGR AHRMIGEQFN MLGEFEKALQ YDRSYLDIAK QEKDHVEVQR AHVTIGRTFL
MKGQSCEKLE QAMEPLMEAE RSFERSLKLS RELKSIGRLE QVDMEARSLL NLGVTKEHQG
NWEQATEYMQ KATKLAENND LTELLHQCYT TSALLFNSKL NNHARALKAL SEALEVASRL
QNKATKMCET LITKADILIK TGDFQSARQA LKQAYKLRTP VATDADNIER RLKVLVAVCR
VEDELIMTGS EEYRKKKGLY ERMGDGACKL ENYAKAIDYY LKMLECAQLA GEADRDLIPI
YVSLYQTYKD NKQYDDALVY LWQEYELIDD DPEEAYNTLL SIADVFEAQK KSWNEVDEIY
QRARAQAKKL KSLPKERVAI KRCVAMLKRQ GMEMMAERLE KEATGMGMDL ENSVAEDSDD
SDTQDETETS IEYAINSLEI GEDVDLAELS NSDDERPKPL DKSLEGKNTR KRGTTFKVKK
NNKGESQLHQ ACIGGNFVLV QKLLDQGHPV NVRDNAGWLP LHEACIHGHK EIVDLLLDRG
AYINDKGGTS CDGITPLYDA CSNGNLEVVE LLLDRGANCT QRTDSGDTTL NVLQLWFEGV
QKKLAPEIIS YYNTIYHRIK GYFDVAAVKP DESATVPDAI LNDSQPAGRS TRRRAIQPIR
SGSESGNEET RSARSTVRNS AKQPSKRRPL PEVRSDSSGL SSDSEPEEQI RPRASKPGVF
DYQTAIEAVR KRTNAQLSPL KDPNPAPSKR TAHMRREEVG DDWLVADVNP ATKRQKFLSD
KDYSEPSVKS SRRSLEDLVS PQKSVASSKG SNRARQRSVS LDPAPDANQI LMSASNRSFS
RAPSAQSKSH RQSLTGSNRY QGSLLEAGFS VSSRSVGSNG SAVDDPEDVR LLMSPSKESV
ASSSGDNRPS GMTTTKAPGL VLPPSMVRVL VDGDQIDVDY DQDQEMGLSV GWLAEEVAKR
YGIKHGKRPL LKLMRSDNSL CMDSEPLSTV LEKTDPVIKS YVIEYTSLRG DQFYEDSCRL
RDLEPVTALM SALNLMENTG KLALKRDFFA GTTRQFDVLF QAIGCQGSTR ELNLSMNQLT
DAELQGFVEK LPVLKNLERL NLAMNPLTQK SIFSMSTKLA SLPDMIYMTE LDLSRCSLLD
QSMPQLASIC QRMPQLRVLR LASTMITNLT YGSPPLDVSR LQVLDVSENS LNKKSIEYMF
AKLDMCILTE LNVCKLGLLA EFKPNLTVAI QTKEFDMLST LNLSQCGLTD DELSTLLVPL
RSSAGKLKLL DVSFNRQLTQ KSFVEVFRTL NTHSLEMVRF AENPLVLKGL SDALMDDIQY
DRARCYPYAV DLMRPLRLGE PEAKTLLDKL TDFWEQLWKE RGAVSMSKST VSLRQKHYT
//
