ID B0W0X4_CULQU Unreviewed; 604 AA.
AC B0W0X4;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDS42791.1, ECO:0000313|EnsemblMetazoa:CPIJ000595-PA};
GN Name=6031605 {ECO:0000313|EnsemblMetazoa:CPIJ000595-PA};
GN ORFNames=CpipJ_CPIJ000595 {ECO:0000313|EMBL:EDS42791.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS42791.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS42791.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ000595-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ000595-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
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DR EMBL; DS231819; EDS42791.1; -; Genomic_DNA.
DR RefSeq; XP_001842358.1; XM_001842306.1.
DR AlphaFoldDB; B0W0X4; -.
DR EnsemblMetazoa; CPIJ000595-RA; CPIJ000595-PA; CPIJ000595.
DR GeneID; 6031605; -.
DR KEGG; cqu:CpipJ_CPIJ000595; -.
DR VEuPathDB; VectorBase:CPIJ000595; -.
DR VEuPathDB; VectorBase:CQUJHB015473; -.
DR eggNOG; KOG1721; Eukaryota.
DR HOGENOM; CLU_452179_0_0_1; -.
DR InParanoid; B0W0X4; -.
DR OMA; CEICARQ; -.
DR OrthoDB; 3456139at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1800.20; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 3.
DR InterPro; IPR012934; Znf_AD.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24406:SF8; C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR24406; TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED; 1.
DR Pfam; PF07776; zf-AD; 1.
DR Pfam; PF00096; zf-C2H2; 1.
DR SMART; SM00868; zf-AD; 1.
DR SMART; SM00355; ZnF_C2H2; 4.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 2.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS51915; ZAD; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 9..85
FT /note="ZAD"
FT /evidence="ECO:0000259|PROSITE:PS51915"
FT DOMAIN 414..441
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 537..564
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 565..588
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 86..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 146..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..110
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..173
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..273
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 11
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 14
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 58
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 61
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
SQ SEQUENCE 604 AA; 66941 MW; BEBEA61916202BD2 CRC64;
MEQSAAVESR CRLCFSADDL TCPLFHSEGD PSREMIDIIL ECTSIQITLE DDYPSRVCEK
CVETLDKFHH YRRRCLENDR ILKSQRSNSS RVRVKQEPEQ LDDEPGSPPT EQRHDQPAQQ
VKQEDSGGSS ILRSILLQVR EAGRAASTAS AELEPEQDVL EFPEPKQEEP PVDEVDAAVA
PSSLLQQMLL QQQTFSRELN QSPAQAGPSH PGPSPSLLKR MLLEGGGAPS PLEGPSHRHD
DQRQTTQSPQ QPPPTNHHHQ QHDENHNEEH SETPLASQLR AILLQHRAAA AAAAAGSAAS
ASTGAATPGE KPEVSYLRSL FLRNDSDGNE DSDSESAVAA ATAAAAAAAD EPSRELLFSM
FQELRARNEL NSDDTDDSAE DRAFDYRIPA VRRRSSESTT TTNAESRKRR RLDFTCLLCG
RPFLNRSKLV LHMRTHIAPP SESVAGASGS GSSGSVTAAA AVMAAAAAAV AGERQAENNE
DDEESRQIEL LERRSYACYI CGADQNNLQQ LKEHLLLAHQ DRIRSRGRAK ERPKPLISCN
FCSRQFRSQF AYGEHLRTHT GERPFPCDQC DKRFPRRFQL LGHLYNVHKQ SWVADESKAK
FVKK
//
