ID B0W0X5_CULQU Unreviewed; 402 AA.
AC B0W0X5;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=ZAD domain-containing protein {ECO:0000259|PROSITE:PS51915};
GN Name=6031606 {ECO:0000313|EnsemblMetazoa:CPIJ000596-PA};
GN ORFNames=CpipJ_CPIJ000596 {ECO:0000313|EMBL:EDS42792.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS42792.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS42792.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ000596-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ000596-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; DS231819; EDS42792.1; -; Genomic_DNA.
DR RefSeq; XP_001842359.1; XM_001842307.1.
DR AlphaFoldDB; B0W0X5; -.
DR EnsemblMetazoa; CPIJ000596-RA; CPIJ000596-PA; CPIJ000596.
DR KEGG; cqu:CpipJ_CPIJ000596; -.
DR VEuPathDB; VectorBase:CPIJ000596; -.
DR VEuPathDB; VectorBase:CQUJHB006879; -.
DR eggNOG; ENOG502RTIM; Eukaryota.
DR HOGENOM; CLU_685621_0_0_1; -.
DR InParanoid; B0W0X5; -.
DR OMA; KRCWAND; -.
DR OrthoDB; 3410601at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1800.20; -; 1.
DR Gene3D; 1.10.10.2590; BEN domain; 1.
DR InterPro; IPR018379; BEN_domain.
DR InterPro; IPR012934; Znf_AD.
DR PANTHER; PTHR39942; BCDNA.LD26519-RELATED; 1.
DR PANTHER; PTHR39942:SF1; RE17222P; 1.
DR Pfam; PF10523; BEN; 1.
DR Pfam; PF07776; zf-AD; 1.
DR SMART; SM00868; zf-AD; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS51915; ZAD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU01263}.
FT DOMAIN 8..84
FT /note="ZAD"
FT /evidence="ECO:0000259|PROSITE:PS51915"
FT REGION 82..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 256..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 358..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 10
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 13
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 57
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 60
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
SQ SEQUENCE 402 AA; 44160 MW; 693A730CE2F3CE46 CRC64;
MTEIEELTRC RLCFSPNNLT DAVFPATGDP NEELMGMIYA CTSVRISFER DFPCAVCSSC
VRIVNQFYAF RRKCRSNDRE LKRTRGEKGF DEGSEEEEDD GGNDPLGSGR MKWEAGGDDR
FYGKMKQQIQ SYLKKQVAEL EKRALAMVRV GLKNTNGGDV SGVQASALQM TVEGAFGGND
MMEQNDSTGY DAFQDYDGDD EPLEDDKSKD DSKNSLLTDG TDWKTKYETL QKNNDLLQKA
FRDQRSKLKD TEQLLKTVKR QKSSGNFTDT SKAPEGVGFK THPAIPEVSL QFLQDLNYKS
GPGEKGDRCF ISKLAVAVFG VDTLVNSSVT GRPSNAHRDL PPKPSLCPQK MAAIGPVRAC
PAGGGRRKPG GAAGPNDGPA RAADRVPKVD ESAQAVFQAQ RQ
//
