ID   B0W3D7_CULQU            Unreviewed;       915 AA.
AC   B0W3D7;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   SubName: Full=Filamin {ECO:0000313|EMBL:EDS31280.1};
GN   Name=6032654 {ECO:0000313|EnsemblMetazoa:CPIJ001681-PA};
GN   ORFNames=CpipJ_CPIJ001681 {ECO:0000313|EMBL:EDS31280.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS31280.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS31280.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ001681-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ001681-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the filamin family.
CC       {ECO:0000256|ARBA:ARBA00009238}.
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DR   EMBL; DS231831; EDS31280.1; -; Genomic_DNA.
DR   RefSeq; XP_001843221.1; XM_001843169.1.
DR   AlphaFoldDB; B0W3D7; -.
DR   STRING; 7176.B0W3D7; -.
DR   EnsemblMetazoa; CPIJ001681-RA; CPIJ001681-PA; CPIJ001681.
DR   KEGG; cqu:CpipJ_CPIJ001681; -.
DR   VEuPathDB; VectorBase:CPIJ001681; -.
DR   VEuPathDB; VectorBase:CQUJHB001300; -.
DR   eggNOG; KOG0518; Eukaryota.
DR   HOGENOM; CLU_339581_0_0_1; -.
DR   InParanoid; B0W3D7; -.
DR   OMA; GWANNYL; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR   InterPro; IPR044801; Filamin.
DR   InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR   InterPro; IPR001298; Filamin/ABP280_rpt.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   PANTHER; PTHR38537:SF18; FILAMIN-A; 1.
DR   PANTHER; PTHR38537; JITTERBUG, ISOFORM N; 1.
DR   Pfam; PF00630; Filamin; 9.
DR   SMART; SM00557; IG_FLMN; 9.
DR   SUPFAM; SSF81296; E set domains; 9.
DR   PROSITE; PS50194; FILAMIN_REPEAT; 9.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT   REPEAT          73..128
FT                   /note="Filamin"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT   REPEAT          128..220
FT                   /note="Filamin"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT   REPEAT          218..308
FT                   /note="Filamin"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT   REPEAT          311..403
FT                   /note="Filamin"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT   REPEAT          401..501
FT                   /note="Filamin"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT   REPEAT          504..596
FT                   /note="Filamin"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT   REPEAT          598..691
FT                   /note="Filamin"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT   REPEAT          693..784
FT                   /note="Filamin"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT   REPEAT          821..915
FT                   /note="Filamin"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
SQ   SEQUENCE   915 AA;  99483 MW;  5D93D19D7AD90CF4 CRC64;
     MWSDEETEPV EASWEEYAQI YRSFEQFMTI SEHDRKQTVR VFHIEQDVPA AEDSVLDFVP
     INMYAAIFIE SHKADIKMPS GEMDKPVIDD NHDGTVSIRY DPKEEGIHEL AVKYNGEHVQ
     GSPFKFHVDS ISSGYVTAYG PGLTHGVTGE PAIFTISTKG AGAGGLQMAV EGPSKADITY
     HDNKDGTVSV SYLPTAPGEY KITVRFGDKH IKGSPYFAKI TGEGRKRNQI SVGSCSEVTL
     PGVISDQDLR SLNASIQAPS GLEEPCFLKR MPSGNIGISF TPREVGEHTV SVKRLGKHIA
     NSPFKVKVCE REVGDAKKVL VTGDALKEGK THADNVFSVD TRNAGYGGLS LSIEGPSKAE
     IQCTDKDDGT LNISYKPTEP GYYIVNLKFA DHHVNGSPFT VKVSGEGTNR QREKIQRQRE
     AVPVTEVGSQ CKLTFKMPGI TSFDLSATVT SPGGVTEDAE IQEIEDGLYA VHFVPKELGV
     HTVSVKYKQI HIPGSPFQFT VGPLKDTGAH LVKAGGPGLE HGEQGVPCEF NVWTREAGGG
     TLAISVEGPS KADIEFKDRK DGSCDVSYLV SEPGDYRIGL KFNDRHIPDS PFKVYVSPAM
     GEAHKLEIAQ FPSGPVQADK PAQFMVRKNG AKGDLDAKVV APSNNEDDCF IQLIDQDQYS
     VRFYPRENGI HAIHVKFNGV HIPGSPYRIK VGKDDVDPAA VHASGKGLGD VKTGEKTDLI
     IDTCNAGAGT LAVTVDGPSK VAMDCTEVEE GYKVRYTPLL PGHYYMTIKY NQMHIVGSPF
     KINCTGEKLA EEGGQETSSV IVETVAKVSK GGNRAGVILP IFKSDASKIQ SKGMGLKKAY
     MGKQNQFTLN AGDAGNNILF VGIYGPKGPC DEVFIKHTGR NQYQVNYLVR ERGDYILLVK
     WGDDHIPGSP FKVEV
//