ID B0W3M2_CULQU Unreviewed; 290 AA.
AC B0W3M2;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=RNA methyltransferase {ECO:0000256|RuleBase:RU367087};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU367087};
GN Name=6032766 {ECO:0000313|EnsemblMetazoa:CPIJ001408-PA};
GN ORFNames=CpipJ_CPIJ001408 {ECO:0000313|EMBL:EDS31808.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS31808.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS31808.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ001408-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ001408-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000256|ARBA:ARBA00008361, ECO:0000256|RuleBase:RU367087}.
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DR EMBL; DS231832; EDS31808.1; -; Genomic_DNA.
DR RefSeq; XP_001843306.1; XM_001843254.1.
DR AlphaFoldDB; B0W3M2; -.
DR STRING; 7176.B0W3M2; -.
DR EnsemblMetazoa; CPIJ001408-RA; CPIJ001408-PA; CPIJ001408.
DR GeneID; 6032766; -.
DR KEGG; cqu:CpipJ_CPIJ001408; -.
DR VEuPathDB; VectorBase:CPIJ001408; -.
DR VEuPathDB; VectorBase:CQUJHB003994; -.
DR eggNOG; KOG2899; Eukaryota.
DR HOGENOM; CLU_004729_2_0_1; -.
DR InParanoid; B0W3M2; -.
DR OMA; ELFRGKQ; -.
DR OrthoDB; 1130801at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR039772; Bin3-like.
DR InterPro; IPR010675; Bin3_C.
DR InterPro; IPR024160; BIN3_SAM-bd_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12315:SF0; 7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME; 1.
DR PANTHER; PTHR12315; BICOID-INTERACTING PROTEIN RELATED; 1.
DR Pfam; PF06859; Bin3; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51515; BIN3_SAM; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000256|RuleBase:RU367087};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU00848};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU367087}.
FT DOMAIN 85..290
FT /note="Bin3-type SAM"
FT /evidence="ECO:0000259|PROSITE:PS51515"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 290 AA; 33278 MW; F25A5DE760E52BC2 CRC64;
MDQTNQPDCG EQLDEAGSRE NVPQNGTSET VKCPEPQKPE VTRDLKRLAG PLTGQTVKRK
KKLFLYGNYD RYYGYRNNRE APKEDVRLPV FMEQRAFIEG KRMLDIGCNN GSLTLLIAEH
CRPASVVGID IDRNLIGAAR NNLAVRQKAC DSEALQNVQF RHINYVYADE ELLECEKPQY
DVIFCLSVTK WIQLNFGDAG VKLAFRRAYR QLHPGGRFVL EPQPWDSYKH RKKLSPEILA
NFRAIQFRPD AFREYLLGDE VGFREVMELK IPSGGAGSKG FRRPIYVFQK
//
