ID B0W4P3_CULQU Unreviewed; 363 AA.
AC B0W4P3;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 78.
DE RecName: Full=Galactose mutarotase {ECO:0000256|ARBA:ARBA00021023};
DE AltName: Full=Aldose 1-epimerase {ECO:0000256|ARBA:ARBA00032729};
GN Name=6033199 {ECO:0000313|EnsemblMetazoa:CPIJ001900-PA};
GN ORFNames=CpipJ_CPIJ001900 {ECO:0000313|EMBL:EDS33888.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS33888.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS33888.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ001900-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ001900-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-galactose = beta-D-galactose; Xref=Rhea:RHEA:28675,
CC ChEBI:CHEBI:27667, ChEBI:CHEBI:28061; EC=5.1.3.3;
CC Evidence={ECO:0000256|ARBA:ARBA00001712};
CC PhysiologicalDirection=right-to-left; Xref=Rhea:RHEA:28677;
CC Evidence={ECO:0000256|ARBA:ARBA00001712};
CC -!- PATHWAY: Carbohydrate metabolism; galactose metabolism.
CC {ECO:0000256|ARBA:ARBA00004947}.
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DR EMBL; DS231838; EDS33888.1; -; Genomic_DNA.
DR RefSeq; XP_001843677.1; XM_001843625.1.
DR AlphaFoldDB; B0W4P3; -.
DR STRING; 7176.B0W4P3; -.
DR EnsemblMetazoa; CPIJ001900-RA; CPIJ001900-PA; CPIJ001900.
DR KEGG; cqu:CpipJ_CPIJ001900; -.
DR VEuPathDB; VectorBase:CPIJ001900; -.
DR VEuPathDB; VectorBase:CQUJHB008415; -.
DR eggNOG; KOG1594; Eukaryota.
DR HOGENOM; CLU_763441_0_0_1; -.
DR InParanoid; B0W4P3; -.
DR OrthoDB; 915361at2759; -.
DR UniPathway; UPA00214; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0004034; F:aldose 1-epimerase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0006012; P:galactose metabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.70.98.10; -; 1.
DR InterPro; IPR008183; Aldose_1/G6P_1-epimerase.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR014718; GH-type_carb-bd.
DR PANTHER; PTHR11122; APOSPORY-ASSOCIATED PROTEIN C-RELATED; 1.
DR PANTHER; PTHR11122:SF39; GLUCOSE-6-PHOSPHATE 1-EPIMERASE; 1.
DR Pfam; PF01263; Aldose_epim; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT REGION 224..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 363 AA; 41036 MW; 54B8212C9DC12AAE CRC64;
MLSRYSTAQF GPWNFGPQHG FARVVRWTLE RSPERLPSGD MEAVFSLMDN EITRSMWNYP
FRITYRLILR EKELHFHIGV YNPSKDITFS FNLLLHTYLK VPDVRRCQIT GLHGCTFIDK
TRDGAIYQEG RDVVTINEWT DRIYQHTPQE HVITNVVSGR KMRLQKYNFP DTVVWNPWMD
KARECQDFGD DEYPNMICVE AGHVSTPVIL LPGTAFEASQ ILQQNQQNQQ NQPQSSSQQQ
NQTTQSNQSS HQQTSHQQQQ QQQQQSQSLA QSSQAAAVAA AAAAAQQQQA AAVQQQQQQQ
QQQQQAAVQQ LWQVPAAAAA AAACWNNYAN FQTAGVLAFK MPPSCGGLCG PQNNCELCSL
NSN
//
