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Database: UniProt
Entry: B0W8G8_CULQU
LinkDB: B0W8G8_CULQU
Original site: B0W8G8_CULQU 
ID   B0W8G8_CULQU            Unreviewed;       246 AA.
AC   B0W8G8;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   20-JUN-2018, entry version 55.
DE   SubName: Full=Deoxynucleoside kinase {ECO:0000313|EMBL:EDS39018.1, ECO:0000313|VectorBase:CPIJ003276-PA};
GN   Name=6034720 {ECO:0000313|VectorBase:CPIJ003276-PA};
GN   ORFNames=CpipJ_CPIJ003276 {ECO:0000313|EMBL:EDS39018.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176 {ECO:0000313|Proteomes:UP000002320};
RN   [1] {ECO:0000313|EMBL:EDS39018.1, ECO:0000313|VectorBase:CPIJ003276-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS39018.1,
RC   ECO:0000313|VectorBase:CPIJ003276-PA};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000002320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|Proteomes:UP000002320};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J.,
RA   Mauceli E., Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L.,
RA   Amedeo P., Antoine C.H., Arensburger P., Bidwell S.L., Crawford M.,
RA   Camaro F., Devon K., Engels R., Hammond M., Howarth C., Koehrsen M.,
RA   Lawson D., Montgomery P., Nene V., Nusbaum C., Puiu D.,
RA   Romero-Severson J., Severson D.W., Shumway M., Sisk P., Stolte C.,
RA   Zeng Q., Eisenstadt E., Fraser-Liggett C.M., Strausberg R.,
RA   Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|VectorBase:CPIJ003276-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|VectorBase:CPIJ003276-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; DS231859; EDS39018.1; -; Genomic_DNA.
DR   RefSeq; XP_001845002.1; XM_001844950.1.
DR   ProteinModelPortal; B0W8G8; -.
DR   STRING; 7176.CPIJ003276-PA; -.
DR   EnsemblMetazoa; CPIJ003276-RA; CPIJ003276-PA; CPIJ003276.
DR   GeneID; 6034720; -.
DR   KEGG; cqu:CpipJ_CPIJ003276; -.
DR   VectorBase; CPIJ003276-RA; CPIJ003276-PA; CPIJ003276.
DR   eggNOG; KOG4235; Eukaryota.
DR   eggNOG; COG1428; LUCA.
DR   HOGENOM; HOG000006872; -.
DR   InParanoid; B0W8G8; -.
DR   KO; K05961; -.
DR   OMA; YNTLQEW; -.
DR   OrthoDB; EOG091G0PXX; -.
DR   PhylomeDB; B0W8G8; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019206; F:nucleoside kinase activity; IEA:InterPro.
DR   InterPro; IPR002624; DCK/DGK.
DR   InterPro; IPR031314; DNK_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01712; dNK; 1.
DR   PIRSF; PIRSF000705; DNK; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002320};
KW   Kinase {ECO:0000313|EMBL:EDS39018.1};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Transferase {ECO:0000313|EMBL:EDS39018.1}.
FT   DOMAIN       19    214       dNK. {ECO:0000259|Pfam:PF01712}.
FT   NP_BIND      22     30       ATP. {ECO:0000256|PIRSR:PIRSR000705-3}.
FT   NP_BIND     158    162       ATP. {ECO:0000256|PIRSR:PIRSR000705-3}.
FT   ACT_SITE     99     99       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000705-1}.
SQ   SEQUENCE   246 AA;  28546 MW;  9834968644A3FF36 CRC64;
     MASASEKLGM RGNKPFTVFI EGNIGSGKTT FLNHFQKFKD RVCLLTEPVE KWRDCGGVNL
     LDLMYKEPNR WAMPFQTYVT LTMLNAHQLQ TDKSIKLMER SMFSARYCFV ENMLASGSLH
     QGMYNILQEW YEFIHANIHI QADLIVYLRT SPEVVYERMM KRARSEESCV PLKYLQELHE
     LHENWLIHGS FPRAAPVLVL DADLDLNNIS SEYKRSETSI LKPILIENTN QHPILASPSK
     RTRTEM
//
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