ID   B0W9C4_CULQU            Unreviewed;       123 AA.
AC   B0W9C4;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   24-JAN-2024, entry version 73.
DE   RecName: Full=Mitochondrial pyruvate carrier {ECO:0000256|RuleBase:RU363100};
GN   Name=6035072 {ECO:0000313|EnsemblMetazoa:CPIJ003735-PA};
GN   ORFNames=CpipJ_CPIJ003735 {ECO:0000313|EMBL:EDS39984.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS39984.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS39984.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ003735-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ003735-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- FUNCTION: Mediates the uptake of pyruvate into mitochondria.
CC       {ECO:0000256|RuleBase:RU363100}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC       inner membrane {ECO:0000256|ARBA:ARBA00004448,
CC       ECO:0000256|RuleBase:RU363100}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU363100}.
CC   -!- SIMILARITY: Belongs to the mitochondrial pyruvate carrier (MPC) (TC
CC       2.A.105) family. {ECO:0000256|ARBA:ARBA00006416,
CC       ECO:0000256|RuleBase:RU363100}.
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DR   EMBL; DS231863; EDS39984.1; -; Genomic_DNA.
DR   RefSeq; XP_001845308.1; XM_001845256.1.
DR   AlphaFoldDB; B0W9C4; -.
DR   STRING; 7176.B0W9C4; -.
DR   EnsemblMetazoa; CPIJ003735-RA; CPIJ003735-PA; CPIJ003735.
DR   KEGG; cqu:CpipJ_CPIJ003735; -.
DR   VEuPathDB; VectorBase:CPIJ003735; -.
DR   VEuPathDB; VectorBase:CQUJHB000437; -.
DR   eggNOG; KOG1590; Eukaryota.
DR   HOGENOM; CLU_099502_3_2_1; -.
DR   InParanoid; B0W9C4; -.
DR   OMA; CTTHFWG; -.
DR   OrthoDB; 3375631at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006850; P:mitochondrial pyruvate transmembrane transport; IEA:InterPro.
DR   InterPro; IPR005336; MPC.
DR   PANTHER; PTHR14154:SF3; MITOCHONDRIAL PYRUVATE CARRIER; 1.
DR   PANTHER; PTHR14154; UPF0041 BRAIN PROTEIN 44-RELATED; 1.
DR   Pfam; PF03650; MPC; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW   ECO:0000256|RuleBase:RU363100};
KW   Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792,
KW   ECO:0000256|RuleBase:RU363100};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363100}.
SQ   SEQUENCE   123 AA;  13729 MW;  31499DCA81AF6B25 CRC64;
     MAALGRKLID SLKSKEFREY LMSTHFWGPV ANWGIPIAAL ADIKKDPKII SGTMTTAVCR
     YSLVFMRVAW RVTPRNLLLF GCHITNFTAQ GLQGGRFVEY HYLGGKTRAV EAPAPTEEKK
     AAK
//