ID B0WA55_CULQU Unreviewed; 425 AA.
AC B0WA55;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 81.
DE SubName: Full=Acid phosphatase-1 {ECO:0000313|EMBL:EDS40884.1, ECO:0000313|EnsemblMetazoa:CPIJ004003-PA};
GN Name=6035388 {ECO:0000313|EnsemblMetazoa:CPIJ004003-PA};
GN ORFNames=CpipJ_CPIJ004003 {ECO:0000313|EMBL:EDS40884.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS40884.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS40884.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ004003-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ004003-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000032};
CC -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
CC {ECO:0000256|ARBA:ARBA00005375}.
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DR EMBL; DS231869; EDS40884.1; -; Genomic_DNA.
DR RefSeq; XP_001845589.1; XM_001845537.1.
DR AlphaFoldDB; B0WA55; -.
DR STRING; 7176.B0WA55; -.
DR EnsemblMetazoa; CPIJ004003-RA; CPIJ004003-PA; CPIJ004003.
DR KEGG; cqu:CpipJ_CPIJ004003; -.
DR VEuPathDB; VectorBase:CPIJ004003; -.
DR VEuPathDB; VectorBase:CQUJHB018323; -.
DR eggNOG; KOG3720; Eukaryota.
DR HOGENOM; CLU_030431_1_1_1; -.
DR InParanoid; B0WA55; -.
DR OMA; IGGWPSY; -.
DR OrthoDB; 5477542at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd07061; HP_HAP_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR033379; Acid_Pase_AS.
DR InterPro; IPR000560; His_Pase_clade-2.
DR InterPro; IPR029033; His_PPase_superfam.
DR PANTHER; PTHR11567:SF110; ACID PHOSPHATASE 1, ISOFORM B; 1.
DR PANTHER; PTHR11567; ACID PHOSPHATASE-RELATED; 1.
DR Pfam; PF00328; His_Phos_2; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
DR PROSITE; PS00778; HIS_ACID_PHOSPHAT_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..425
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011407698"
FT TRANSMEM 385..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 425 AA; 48074 MW; B563DBAA905D4436 CRC64;
MARLLTLLVA TLLWLHVANS QQVQSEDKLI FAHVLYRHGD RTPIDPYPND PWKDPAHWTA
GWGQLTNDGK HRHLELGRWL RKRYGSLLGA TYTNNEIYVR STDVDRTLMS AESNLAGLYP
PVGPDRWDAA IQWQPIPVHT VPEELDEVLA AKKPCSAFDL ELKKYKHTDE FQAYNKSLEP
LYEYVTAHSG RAVDSLTSAQ NIYSCLHIEE LNNFTLPAWT VKVYPEPLRS ISAKSFATKT
NTPLMARLKA GPLVKEILER FRAKLNRKLK PDRSVWVYSA HDTTVANLLN ALRVFDLHNP
PFAACVLLEL RQPSGGAEPY VSVYYKNSSA EPTLLTVPNC GQRCPLSQTF KVYQDILPES
WKRECQVSFL SLTYVEADVG TSGGMIGLVL VASVAVLGLV IALLTLYRRR RGGYHNDKWY
LRIDG
//
