ID B0WA78_CULQU Unreviewed; 1578 AA.
AC B0WA78;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Myosin vii {ECO:0000313|EMBL:EDS40907.1, ECO:0000313|EnsemblMetazoa:CPIJ004026-PA};
GN Name=6035419 {ECO:0000313|EnsemblMetazoa:CPIJ004026-PA};
GN ORFNames=CpipJ_CPIJ004026 {ECO:0000313|EMBL:EDS40907.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS40907.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS40907.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ004026-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ004026-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
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DR EMBL; DS231869; EDS40907.1; -; Genomic_DNA.
DR RefSeq; XP_001845612.1; XM_001845560.1.
DR STRING; 7176.B0WA78; -.
DR EnsemblMetazoa; CPIJ004026-RA; CPIJ004026-PA; CPIJ004026.
DR KEGG; cqu:CpipJ_CPIJ004026; -.
DR VEuPathDB; VectorBase:CPIJ004026; -.
DR VEuPathDB; VectorBase:CQUJHB014648; -.
DR eggNOG; KOG0248; Eukaryota.
DR eggNOG; KOG4229; Eukaryota.
DR HOGENOM; CLU_006586_13_2_1; -.
DR InParanoid; B0WA78; -.
DR OMA; ICDINEM; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0071944; C:cell periphery; IEA:UniProt.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0009887; P:animal organ morphogenesis; IEA:UniProt.
DR GO; GO:0030182; P:neuron differentiation; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 2.
DR CDD; cd17208; FERM_F1_DdMyo7_like; 2.
DR Gene3D; 1.20.80.10; -; 2.
DR Gene3D; 1.25.40.530; MyTH4 domain; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46049; AGAP003327-PA; 1.
DR PANTHER; PTHR46049:SF5; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3; 1.
DR Pfam; PF00373; FERM_M; 2.
DR Pfam; PF00784; MyTH4; 2.
DR Pfam; PF00788; RA; 2.
DR SMART; SM00295; B41; 2.
DR SMART; SM00139; MyTH4; 2.
DR SMART; SM00314; RA; 2.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR SUPFAM; SSF47031; Second domain of FERM; 2.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50057; FERM_3; 2.
DR PROSITE; PS51016; MYTH4; 2.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 432..582
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 587..939
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT DOMAIN 1029..1189
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 1192..1300
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 1194..1503
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 146..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 299..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1506..1578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..178
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..345
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1506..1520
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1530..1544
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1562..1578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1578 AA; 178601 MW; 5010D85F5D1C7F41 CRC64;
MAEQINSKLH SQQQQHAANN NNNNANQINN NNKGKDRPEV NGGDGGGSPA PAGIASANHA
HQQSNESVDL DNLFAFLSEV QPNGANSNAI IDEIGEKMDN LVEDLDVELE SVIQQEIEGL
TSERNNNISG KSAILNGANN NNNNTMLGNK PTTPKPMGVP SLPEPTMPPP PIPTENNNSA
LPPPSAASVP SSLDHHHMRH NREEPIYEAV IHLKELPPPP EIHEKVPPVP QHTLSATQSH
SATLQHQQQQ LAAAQQQQLQ QQLQQQQQQS NHAPPPPPHA HGVIHQPMQQ PQTLLENGTA
GHKLRPKSPA VIRSASPIQR GTTGGPMSPS SPKHSRPNSR ASSTGAGHPF AEREQRRKYR
VEKKLQEMQQ MDITEREKEL LRDDVYHDIL EFAESYYNTH ERSPEGTIMA TLTRKGRKSV
DMVPKYEMIT YYRGNTIPSS HIHMYDPENV TIACNIFRDL CKYIRGELNN ERELQVIQFI
IGQGIEREEL RDEIFVQCMR QATNNPSVEW TDRVWLLLCL TIVAFQPSKL LFRYFCSFLK
KNLETLEGKL RQYVQWCLDN CKNTKVRCRQ YAPSSVEIAA MRRLGTIVCR FFFLDGRTKA
IDVHPTDTAS DAVAKLAEKL GLCNIEGWAI YQSRPDGEEH VKSHDYLYDI IAAWESARDR
GCRQSNIVKK VNRRAYRIFL YLKLPDDKQT KIHAGSSTLR KNATTLGSGE NRFVFKKRLF
KSTRELSQDP VEVNMLYAQA VYSVVKCDDF PVSEKVALQL AGLQAQVALG DPSNQPKPEY
YSDVASFLPE RISSCREEQF WVPILAQAHR QYGSGRTELT AKVLYLSCVM QYPLYGTTMF
PVSYRGYWSY GNSLILGVNC EGIILIKPDD KFVLYEFRYS EIESIMLDPS DSFITISLNR
HTSTTTTADQ QRCFVFETSQ KNEIGSLIVS YFPALSNWIT ENEVPPKKSK GITNEDRVRL
HHNVVVCRRH LVDAEILRKP QDPSGGFLRN TLRRLSKHRL EKLRAEHGHG SVHDHGETYK
GFPHAYWAFS RQALPQSLSK IPDQEEQAMI QVFNSILTYA GLGQNGETVQ RAEDEHITLI
QSIMDRCMRK ESLLNELYLQ LIKQTTDHPD PNSRVNLRHW ALLSLACSVI LPPQKVVRKY
LIGHLKRCAS DFITEEGKYA RFAEKCFFKT QGTRRRQWPP SREEIVCTIN RRPIYARFHF
MDGQYHSVEF HPSSTSREVM EIVKKKIGLQ ENAQGYAIYE VLGASERSLL PDEKVADVMS
KWEKYRTAAA QAVQQNQSSS NLAPACRRQH HLFLFKKHLF CDQYMNLDDP VEKELLYHQV
LHGLRTERFP ISEMEAVMLT ALQGQLELGD CSEVVQDYRA IAAHCLPPRF VPNIPHEGVA
MHHQSLRGMT SAEAKKSFLN LIQSWPLHKA TIFDVMQSFT SNWPRILWLA VDQKGLHLLE
HRSRNTLCTY EYQSILSFSP NMNCLMIITG SDKKQSKVIL TTAQAFQIAN LIREYMEVMN
SNAQLSDDSQ KENTNNGNVM GAGAPGVPHV PPHHNQPLPP PHGAVQQPDL RKGPGGGQRP
PSMVLRQSNA ALVAPQPS
//
