ID   B0WBU4_CULQU            Unreviewed;      1112 AA.
AC   B0WBU4;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   24-JAN-2024, entry version 89.
DE   SubName: Full=Raptor1a {ECO:0000313|EMBL:EDS42874.1, ECO:0000313|EnsemblMetazoa:CPIJ004643-PA};
GN   Name=6036085 {ECO:0000313|EnsemblMetazoa:CPIJ004643-PA};
GN   ORFNames=CpipJ_CPIJ004643 {ECO:0000313|EMBL:EDS42874.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS42874.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS42874.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ004643-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ004643-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the WD repeat RAPTOR family.
CC       {ECO:0000256|ARBA:ARBA00009257}.
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DR   EMBL; DS231882; EDS42874.1; -; Genomic_DNA.
DR   RefSeq; XP_001846178.1; XM_001846126.1.
DR   AlphaFoldDB; B0WBU4; -.
DR   STRING; 7176.B0WBU4; -.
DR   EnsemblMetazoa; CPIJ004643-RA; CPIJ004643-PA; CPIJ004643.
DR   KEGG; cqu:CpipJ_CPIJ004643; -.
DR   VEuPathDB; VectorBase:CPIJ004643; -.
DR   VEuPathDB; VectorBase:CQUJHB009827; -.
DR   eggNOG; KOG1517; Eukaryota.
DR   HOGENOM; CLU_001136_3_1_1; -.
DR   InParanoid; B0WBU4; -.
DR   OrthoDB; 3452613at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0031931; C:TORC1 complex; IEA:InterPro.
DR   GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR004083; Raptor.
DR   InterPro; IPR029347; Raptor_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR12848; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR   PANTHER; PTHR12848:SF16; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR   Pfam; PF14538; Raptor_N; 1.
DR   Pfam; PF00400; WD40; 1.
DR   PRINTS; PR01547; YEAST176DUF.
DR   SMART; SM01302; Raptor_N; 1.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT   DOMAIN          24..183
FT                   /note="Raptor N-terminal CASPase-like"
FT                   /evidence="ECO:0000259|SMART:SM01302"
FT   REGION          586..621
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1079..1112
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1084..1112
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1112 AA;  123827 MW;  BF5463744C876B12 CRC64;
     MKAWSDKSRL VKCHRDRLGS NPSRLDSLLL TSAHLNTAIQ TVDVAGWELT ERTNAWINLL
     CLEDDSTAKL LRSERRHFQS FDREHSHYFR SRFRSLPDVC VTDLRSACDQ LKAHEWPVVH
     YCGHSVDQRP ARRPEVAASF WCNDDRYQKL VEVSVAEVGE WLRMPAVFIV ECNSAQTVLD
     GLPEDGDGSL YLGVCGRGER LPFRGGVRKD LFGCLLTCPV KTAVELHRCK LGKKGQPLER
     LPGHLPNRKM LLGQLDWVLT LMLDAIGERT LPVELFEQLF RGDLMVATMF RRFLLAQRTL
     PTYGCNPVSK PELPNCAQDG LWAVWDKLLD RAVDLLEAQD ERECRLVEMF FRLVLEEDKG
     TYLPFIPHAL TVPQQSVSAL DKLSNCWPEV QADPKLQQFV FAGLMELLKS NEDPQIFAKA
     INSAMKLLTI NLENIPSLKQ LEMVNLIGKL PAEFSDDLVV KTIVLQLLAE QSSEEKDSQG
     CQLLQNSCEK LLEHSNADIR LWSILLMTKI GSNHPSLESL LTDPVPKVRT AAMTGWIAAN
     LDKKDVLLDK IVSLIPTNSS CVVRRELAHA LNAAANQRLP ELVTSCKQES IKQPEPAKSA
     AKAKAKSKQK KPPTAVSTTS SEAVMTRAWS CLKTLQNDPD PEVAGAVRSL VNLVRQKVNA
     NGNDAGKKAK KKLAAQEANA MLLPARESYR ERCLREFLEK VAAPPQVVEE DKENHSRLAN
     GVENSRNPTM ALLNHQLRHL QTKRAPEMVR FGPQRQLAIP FKECVSWQDY DGEAVHNLKP
     TPSATGNGDT AHPVTSLLFQ SASNLLVGHR DGVVRMWRST DQESPTLINA WQALYDHETP
     TPPKPVNPVM TTIDNRKLLI GGDSKHIRCW DLNQEVLSED LPSDHGTITA MTNHGHNLAV
     GTADGAVRLY DLRAPNKVAT AAPKHAKPPK VISFRPNDEH TLVSVCAAGS VHVLDTRKMT
     PVKTWSIPEL ALPEVAIHER LNLVATCSAE VVEVYTVEGK EVARVDRNDV GEGVPVVVGG
     AVGKKRPPTC VAFHGTELLM CAGYKDNMAV LFGEKAHVVL LQEEKVSASV EYRNCGEPQA
     RASEIPDGRQ KSRSASRTHR EEWISDGFWE KM
//