ID B0WD85_CULQU Unreviewed; 486 AA.
AC B0WD85;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=Tnf receptor associated factor {ECO:0000313|EMBL:EDS44357.1, ECO:0000313|EnsemblMetazoa:CPIJ005312-PA};
GN Name=6036684 {ECO:0000313|EnsemblMetazoa:CPIJ005312-PA};
GN ORFNames=CpipJ_CPIJ005312 {ECO:0000313|EMBL:EDS44357.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS44357.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS44357.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ005312-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ005312-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; DS231895; EDS44357.1; -; Genomic_DNA.
DR RefSeq; XP_001846690.1; XM_001846638.1.
DR AlphaFoldDB; B0WD85; -.
DR STRING; 7176.B0WD85; -.
DR EnsemblMetazoa; CPIJ005312-RA; CPIJ005312-PA; CPIJ005312.
DR KEGG; cqu:CpipJ_CPIJ005312; -.
DR VEuPathDB; VectorBase:CPIJ005312; -.
DR VEuPathDB; VectorBase:CQUJHB017154; -.
DR eggNOG; KOG0297; Eukaryota.
DR HOGENOM; CLU_021061_6_0_1; -.
DR InParanoid; B0WD85; -.
DR OMA; HSNCATS; -.
DR OrthoDB; 2913784at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR002083; MATH/TRAF_dom.
DR InterPro; IPR012227; TNF_rcpt-assoc_TRAF_met.
DR InterPro; IPR008974; TRAF-like.
DR InterPro; IPR049342; TRAF_MEP1_MATH_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR PANTHER; PTHR10131:SF144; TNF RECEPTOR-ASSOCIATED FACTOR 4; 1.
DR Pfam; PF21355; TRAF-mep_MATH; 1.
DR Pfam; PF02176; zf-TRAF; 2.
DR PIRSF; PIRSF015614; TRAF; 1.
DR SMART; SM00061; MATH; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 4.
DR PROSITE; PS50144; MATH; 1.
DR PROSITE; PS50145; ZF_TRAF; 3.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Receptor {ECO:0000313|EMBL:EDS44357.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 124..177
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 179..230
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 232..290
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 330..478
FT /note="MATH"
FT /evidence="ECO:0000259|PROSITE:PS50144"
FT ZN_FING 124..177
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT ZN_FING 179..230
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT ZN_FING 232..290
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT REGION 19..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 486 AA; 53588 MW; BD2D4D2E808EEC25 CRC64;
MVRSLSQWTK TLSFPARISP NRNSKDCSVN VLPITPPPAP PRNKPATSTT TCSSSNSSTM
SSPSPPPNVP ITEISQIVTP ILSLLPFQIY PDPESEKAIM GSLVFCIHHK QGCKWSDELR
KLKAHLNTCK HDAIPCPNKC GSQIPRVMMT DHLAFTCILR RAICEFCNVE FTGLGLEEHA
GTCSSEPMYC ESKCGARVVR GRMSIHRAKD CSKRLRRCPH CSREFSADTL SAHGATCPRS
PVPCPQRCDA GPMARADLDS HLRDECKALS VPCSFKDAGC RFKGPRHLLE AHLESNTSAH
LSLMVALSGR QGQQITMLKN AMAKLSTNYT GTLLWKITDW SAKMVEAKSK DGLELVSPPF
YTSQYGYKLQ ASMFLNGNGP GESTHVSVYI KVLPGEYDAL LKWPFSHSVT FTLFEQGTLG
GQGGVAESFV PDPSWENFQR PSSEPDALGF GFPRFVSHEL LNRRPFVRED TVFLRVKVDP
SKIVAV
//
