ID   B0WEF6_CULQU            Unreviewed;       583 AA.
AC   B0WEF6;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 67.
DE   RecName: Full=ZP domain-containing protein {ECO:0000259|PROSITE:PS51034};
GN   Name=6037155 {ECO:0000313|EnsemblMetazoa:CPIJ005428-PA};
GN   ORFNames=CpipJ_CPIJ005428 {ECO:0000313|EMBL:EDS45616.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS45616.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS45616.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ005428-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ005428-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   EMBL; DS231909; EDS45616.1; -; Genomic_DNA.
DR   RefSeq; XP_001847090.1; XM_001847038.1.
DR   AlphaFoldDB; B0WEF6; -.
DR   STRING; 7176.B0WEF6; -.
DR   EnsemblMetazoa; CPIJ005428-RA; CPIJ005428-PA; CPIJ005428.
DR   KEGG; cqu:CpipJ_CPIJ005428; -.
DR   VEuPathDB; VectorBase:CPIJ005428; -.
DR   VEuPathDB; VectorBase:CQUJHB001348; -.
DR   eggNOG; ENOG502QV6H; Eukaryota.
DR   HOGENOM; CLU_030913_0_0_1; -.
DR   InParanoid; B0WEF6; -.
DR   OMA; ESCACFC; -.
DR   OrthoDB; 3660364at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.4100; Zona pellucida, ZP-C domain; 1.
DR   InterPro; IPR042235; ZP-C.
DR   InterPro; IPR001507; ZP_dom.
DR   PANTHER; PTHR46560; CYPHER, ISOFORM B; 1.
DR   PANTHER; PTHR46560:SF3; ZP DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00100; Zona_pellucida; 1.
DR   SMART; SM00241; ZP; 1.
DR   PROSITE; PS51034; ZP_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        536..558
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          238..478
FT                   /note="ZP"
FT                   /evidence="ECO:0000259|PROSITE:PS51034"
FT   REGION          39..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          129..173
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          197..216
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        59..102
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        149..171
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   583 AA;  64034 MW;  29EE939C440A7674 CRC64;
     MYNRKNPTGA GTTVVPVLFQ TSNNGLTAPV TASALTTAGR GSISSTVAPK VQRKRGSSGK
     KSIVISQPID SANNSRESLS HEGSEPALAS AHSTENPTGA GTTVVPVLFQ TSNNGLTAPV
     TASALTTAGR GSISSTVAPK VQRKRGSSGK KSIVISQPID SANNSRESLS HEGSEPVVYV
     SDSSGYIPLT SLQSATHSRL PPSYQQESDP AWRPDPWDRD YNRRHRFNNT RVQHIEAECQ
     DDYMKIRIGF NGSFSGLLYS SGYAYDPDCM YINGSGRDYY EFLIQLNRCG TLGKNANGDD
     SRKNPTKNFM WNTVTVQYNP LIEEEFDEHF KVTCEVATGN PVVFTLSPPE CYMEIRNGYG
     TNGARVTGPV RVGDPLTLII YMRSKYDGFD IVVNDCVAHN GANKRIQLID EYGCPVDDKL
     ISRFRGSWSD GGLYETQVYA YMKTFRFTGS PALYIECDVR MCHGRCPSQP CHWRNLKGIT
     KRETPQENNS TLSDNISLFQ ALRVLQEEDD EAKQNKEAST STKPQDMSET CVKTSILSAM
     LATCCVVLCV LSGSLLAACA KLRYRKKDEA FFNTYVGHKA QLD
//