ID B0WH32_CULQU Unreviewed; 1512 AA.
AC B0WH32;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Leucine-rich transmembrane protein {ECO:0000313|EMBL:EDS27483.1, ECO:0000313|EnsemblMetazoa:CPIJ006310-PA};
GN Name=6038186 {ECO:0000313|EnsemblMetazoa:CPIJ006310-PA};
GN ORFNames=CpipJ_CPIJ006310 {ECO:0000313|EMBL:EDS27483.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS27483.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS27483.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ006310-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ006310-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; DS231932; EDS27483.1; -; Genomic_DNA.
DR RefSeq; XP_001848016.1; XM_001847964.1.
DR STRING; 7176.B0WH32; -.
DR EnsemblMetazoa; CPIJ006310-RA; CPIJ006310-PA; CPIJ006310.
DR KEGG; cqu:CpipJ_CPIJ006310; -.
DR VEuPathDB; VectorBase:CPIJ006310; -.
DR VEuPathDB; VectorBase:CQUJHB011243; -.
DR eggNOG; KOG0619; Eukaryota.
DR HOGENOM; CLU_001410_1_0_1; -.
DR InParanoid; B0WH32; -.
DR OMA; GNWINAI; -.
DR OrthoDB; 3437167at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45712; AGAP008170-PA; 1.
DR PANTHER; PTHR45712:SF22; LEUCINE RICH REPEAT FAMILY PROTEIN; 1.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF13855; LRR_8; 9.
DR SMART; SM00364; LRR_BAC; 10.
DR SMART; SM00365; LRR_SD22; 11.
DR SMART; SM00369; LRR_TYP; 34.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF52058; L domain-like; 3.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 5.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:EDS27483.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1391..1416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 47..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1512 AA; 171107 MW; 7F1308F19255126C CRC64;
MMLRWWPNLG LTQPYYKYLW RCWLLVGLIL LQRISYGQME EILRLRGGGQ GSGGGGGGSG
HHGHHQQQHL QQLDEQEHHF SSASSNEIEC PSFVDNSACP CYKFEDVYEF DRSVKSLTVD
LFAPANQQSS DVNIRHLQFS NSNLQQLKEN SLSNLRAHLE SLSIVNGKLT QVPTKALAGL
KKLMVLDFEL NEISAIEEYA FYGLHLVKLN MKGNRLERIP ENAFSGLEDS LAELDLSENR
LKQFPTGALK RLENLRSVRL SMNEINSLEQ DDSYTRFGSL VFLDLSLNNF VELYSDVFNP
FPYVKTLSLY NNFIELVHRD SFVSLKELQS LDLSHNQVVF VDPEVFSANR KLHTVDLSHN
HIHYVSGVFA NLPLLREIFL SENNILELTD DCFSNSSSIK VIYLENNSLQ RLGSDTLATL
TNLEQLYLSG NHIQRIPVGF FETTVKLQSL SLDGNELTEL DVRLFRRLAN LREVRLNGNQ
LRSIREHLFA AQENMMELHL QNNVISLIER NAFKNCLQLQ YINLQENELD EIDILLSTTA
STDSANQQPL TARGKLITTK TDPGSFGDPQ DSLTSSSLIS IQLNSNSIKY LHGHSFQGQG
SVQIIWLENN LLKSLDKMLF ADLFQLERLY LRNNTLTSIE YGALDSLRRL RYLDLSVNRL
STLNEQLFRS LAELDELHLG DNQIENLGPN VFSSLRKLRV LDISDNPLGT LQKDVFQPNL
SVSMINLKSC GLSRIEANTF RGLQNLNELN LEDNRLRADD VRQIDVSSLR TLRLSSNNFT
VIRENMLDRL PSLQNLVLDR CSIRELPATL FSKNNNLVKL DLSNNYLRTL KRNTFNNLNV
FKELRLHNNQ INDFPHVALS NVSTLELLSL SKNQLTSVDF YKLHGLPNLR HLDFRDNTIS
SLSGFNTVTL PHLDMIDLSG NLLLALPQNF FKHSISLQRI DLSCNRFNQI PNAALSESSL
ARLAWLNLTG NPLQRIHHTM TAADDQHRKY PHLKELHISQ TNLTILTSKD FEIYPALQRL
YLIQNRINRV SPGAFVALSN LQILDLSVNE IEILPKERLQ GLKLLEILNI STNNIKELDE
FTDDLQKLKI LDISSNQLER IHKNTLRYLV ALQELHLYGN RIVSISSDAF RTLRNLKALD
IRKNYFEAIP LRALKPLETH LKELRVGENP LLCNCETQEL WEWLGDHRKW TSTGYGGVRC
EQPVEIQGKG LLAMEPQEFC DKPLILKIAI QDIRPYSVLV SWQSREHSGL HGYHVIFHSL
DTVEDIRGKT LNRQANSAQL DRLSANTRYL ICVLGLGNWL SGYHDHDIHS LLNQSNQIQN
QVLNGPHGYG VDGGNELDTS LSNSLLSLMM DTPTSRCTEV RTLDAIGPNP LAEVDGMSSR
SIIHSILTRR LGLIVGCCLG IVVFIVLISV LGYLKIKKQR LDAAKRLQQP PMAPEFISYR
HFSIPNDEHG RDGVAPGGGT NTFLQGAAVV ANHDGHPSFI SGAVLGTTTT LNGGAGTGLV
PGEERKKIMF DS
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