GenomeNet

Database: UniProt
Entry: B0WH58
LinkDB: B0WH58
Original site: B0WH58 
ID   CUE_CULQU               Reviewed;         658 AA.
AC   B0WH58;
DT   13-OCT-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   16-JAN-2019, entry version 63.
DE   RecName: Full=Protein cueball {ECO:0000250|UniProtKB:Q95RU0};
DE   Flags: Precursor;
GN   Name=cue {ECO:0000250|UniProtKB:Q95RU0}; ORFNames=CPIJ006575;
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000312|EMBL:EDS27565.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000312|EMBL:EDS27565.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J.,
RA   Mauceli E., Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L.,
RA   Amedeo P., Antoine C.H., Arensburger P., Bidwell S.L., Crawford M.,
RA   Camaro F., Devon K., Engels R., Hammond M., Howarth C., Koehrsen M.,
RA   Lawson D., Montgomery P., Nene V., Nusbaum C., Puiu D.,
RA   Romero-Severson J., Severson D.W., Shumway M., Sisk P., Stolte C.,
RA   Zeng Q., Eisenstadt E., Fraser-Liggett C.M., Strausberg R.,
RA   Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Has a role in spermatogenesis and oogenesis.
CC       {ECO:0000250|UniProtKB:Q95RU0}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass
CC       type I membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cueball family. {ECO:0000305}.
DR   EMBL; DS231933; EDS27565.1; -; Genomic_DNA.
DR   RefSeq; XP_001848072.1; XM_001848020.1.
DR   ProteinModelPortal; B0WH58; -.
DR   STRING; 7176.CPIJ006575-PA; -.
DR   PRIDE; B0WH58; -.
DR   EnsemblMetazoa; CPIJ006575-RA; CPIJ006575-PA; CPIJ006575.
DR   GeneID; 6038248; -.
DR   KEGG; cqu:CpipJ_CPIJ006575; -.
DR   VectorBase; CPIJ006575-RA; CPIJ006575-PA; CPIJ006575.
DR   eggNOG; KOG1215; Eukaryota.
DR   eggNOG; ENOG410XP34; LUCA.
DR   HOGENOM; HOG000045594; -.
DR   InParanoid; B0WH58; -.
DR   OMA; ETPCFDP; -.
DR   OrthoDB; 520442at2759; -.
DR   PhylomeDB; B0WH58; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0048477; P:oogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 2.120.10.30; -; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR013032; EGF-like_CS.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR000033; LDLR_classB_rpt.
DR   SMART; SM00181; EGF; 5.
DR   SMART; SM00135; LY; 5.
DR   PROSITE; PS00022; EGF_1; 5.
DR   PROSITE; PS01186; EGF_2; 1.
DR   PROSITE; PS50026; EGF_3; 3.
PE   3: Inferred from homology;
KW   Cell membrane; Complete proteome; Differentiation; Disulfide bond;
KW   EGF-like domain; Glycoprotein; Membrane; Oogenesis;
KW   Reference proteome; Repeat; Signal; Spermatogenesis; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL        1      ?       {ECO:0000255}.
FT   CHAIN         ?    658       Protein cueball. {ECO:0000255}.
FT                                /FTId=PRO_0000386568.
FT   TOPO_DOM      1    543       Extracellular. {ECO:0000255}.
FT   TRANSMEM    544    564       Helical. {ECO:0000255}.
FT   TOPO_DOM    565    658       Cytoplasmic. {ECO:0000255}.
FT   REPEAT      100    142       LDL-receptor class B 1. {ECO:0000255}.
FT   REPEAT      152    195       LDL-receptor class B 2. {ECO:0000255}.
FT   REPEAT      196    241       LDL-receptor class B 3. {ECO:0000255}.
FT   DOMAIN      352    384       EGF-like 1. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00076}.
FT   DOMAIN      387    422       EGF-like 2. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00076}.
FT   DOMAIN      458    495       EGF-like 3. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00076}.
FT   CARBOHYD     25     25       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    122    122       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    400    400       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    415    415       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    476    476       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    541    541       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   DISULFID    356    365       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    360    375       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    391    401       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    395    410       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    412    421       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    462    472       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    466    483       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    485    494       {ECO:0000255|PROSITE-ProRule:PRU00076}.
SQ   SEQUENCE   658 AA;  74118 MW;  19BFDB063361CA8E CRC64;
     MSGVTARMEN SIITTDSGIL FFDQNWTQVS SGGHQFQHIS AFAYDEVKQK LYFSDLKDPK
     FRIFSLDANP QEEYHKVTKL LPKSDETAYI TGLVFDHLER KLYWTERGTH ALYSVEVDKI
     GNGTDAGSLI STVTKVEDNH DLAGLAIDEC RRHLYWTNSY LQTSNVVRAT MAGKVLNSHT
     EDVYEPKGIA VDHYSNRIYW VEKKFGRAFS IQSVNLEVED VKTFISENDK APTHVALNSR
     YLYWVDQQVG EVHETLKSDS TQSRVVYRGN RPTAIIIKSA LLLNHQNNNP SCKSVIAKIL
     DNVKRESEGE LPQADKPTSA KPEMIICLNN GILNHNTNSC ICLPEYQGNF CEIPICNNYC
     VHGKCVIGRD NRPTCECDAK FEGERCDRSK CDGFCLNSGN CSFSDATATC ACPKNFSGKR
     CETAICTSDY CYNGRCMVEE GGSPKCQCNV GYRGERCEEY TCNNYCLNDG KCVLNNETML
     VECRCGAEYT GKRCEIPKRF CSLDTGNPEL QPYCDGIPLS SQQQQQQLVE PQISYCKNSF
     NRTVVYASLA FAASLFILMV ILLIVRRFYE EGRPRITKRF KVTSNHTQMT SRPATQCEIT
     IENCCNMNVC ETPCFDTNLL QKSSSKAEDK QYLLDDIENI AGSYRKLPSC AGGDKNLP
//
DBGET integrated database retrieval system