ID   B0WHM7_CULQU            Unreviewed;       534 AA.
AC   B0WHM7;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Anion exchange protein 2, slc4a2 {ECO:0000313|EMBL:EDS27876.1, ECO:0000313|EnsemblMetazoa:CPIJ006527-PA};
GN   Name=6038405 {ECO:0000313|EnsemblMetazoa:CPIJ006527-PA};
GN   ORFNames=CpipJ_CPIJ006527 {ECO:0000313|EMBL:EDS27876.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS27876.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS27876.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ006527-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ006527-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS231938; EDS27876.1; -; Genomic_DNA.
DR   RefSeq; XP_001848211.1; XM_001848159.1.
DR   AlphaFoldDB; B0WHM7; -.
DR   STRING; 7176.B0WHM7; -.
DR   EnsemblMetazoa; CPIJ006527-RA; CPIJ006527-PA; CPIJ006527.
DR   KEGG; cqu:CpipJ_CPIJ006527; -.
DR   VEuPathDB; VectorBase:CPIJ006527; -.
DR   VEuPathDB; VectorBase:CQUJHB014981; -.
DR   eggNOG; KOG1172; Eukaryota.
DR   HOGENOM; CLU_510255_0_0_1; -.
DR   InParanoid; B0WHM7; -.
DR   OrthoDB; 1013180at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR   InterPro; IPR013769; Band3_cytoplasmic_dom.
DR   InterPro; IPR003020; HCO3_transpt_euk.
DR   InterPro; IPR016152; PTrfase/Anion_transptr.
DR   PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR   PANTHER; PTHR11453:SF47; ANION EXCHANGE PROTEIN; 1.
DR   Pfam; PF07565; Band_3_cyto; 1.
DR   SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT   DOMAIN          432..530
FT                   /note="Band 3 cytoplasmic"
FT                   /evidence="ECO:0000259|Pfam:PF07565"
FT   REGION          167..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          267..377
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        171..233
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        318..332
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        341..359
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        363..377
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   534 AA;  60376 MW;  0EBCC45AE8D88BD2 CRC64;
     MKASNGLAVL SRLLNPCSKN PRIRTTRVHK TSINIEHWKP RRRRDVTHGD DCRIDKFGCS
     GPGGSRWASS TRIRRKDLSG DAHTALHPTK PPRAVPHQLM WDDSRTEIYS LATTSRDYRI
     TPTTSNNDPD QVQLDDEMEK VFGSVGTDKE KFELKRLNDD VLVDQSPLKY EETSRPATTS
     LRPMDTSGAS GANNGSSLPS TTPTSPISMS SKSESAAPKP SNDTTLADNS SNDFSEVVHD
     DPPPVVDQGS TLQGEQWDNS ARRNVRFDSQ DQPAQFVGLQ IEDTNEERRR RTERHHPHKS
     RKFSLQEYHP EWRRQSGAEG ASTGTRRVSV QPEDATLQEA DIDELTSHRS DDPRALRRHK
     VSAQSASGVS ASVVSTNRKD NDKLDQLLSS SKCKKLYDHS PHEVFVQLDE LTGTGEEREW
     KETARWIKYE EDVEEGADRW GRPHVASLSF HSLLNLRRCL ETGVVLMDLD EKDLPSVAYR
     IVEQMVTDEL IHEDDKPVIM RALLLRHRHV NEHSHGGFHF GPKRKYSSYS SLQK
//