ID   B0WIR0_CULQU            Unreviewed;       225 AA.
AC   B0WIR0;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 85.
DE   SubName: Full=Adenylate kinase isoenzyme {ECO:0000313|EMBL:EDS28637.1, ECO:0000313|EnsemblMetazoa:CPIJ007065-PA};
GN   Name=6038895 {ECO:0000313|EnsemblMetazoa:CPIJ007065-PA};
GN   ORFNames=CpipJ_CPIJ007065 {ECO:0000313|EMBL:EDS28637.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS28637.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS28637.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ007065-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ007065-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the adenylate kinase family.
CC       {ECO:0000256|ARBA:ARBA00007220, ECO:0000256|RuleBase:RU003330}.
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DR   EMBL; DS231951; EDS28637.1; -; Genomic_DNA.
DR   RefSeq; XP_001848594.1; XM_001848542.1.
DR   AlphaFoldDB; B0WIR0; -.
DR   STRING; 7176.B0WIR0; -.
DR   EnsemblMetazoa; CPIJ007065-RA; CPIJ007065-PA; CPIJ007065.
DR   KEGG; cqu:CpipJ_CPIJ007065; -.
DR   VEuPathDB; VectorBase:CPIJ007065; -.
DR   VEuPathDB; VectorBase:CQUJHB017095; -.
DR   eggNOG; KOG3079; Eukaryota.
DR   HOGENOM; CLU_1230978_0_0_1; -.
DR   InParanoid; B0WIR0; -.
DR   OrthoDB; 1330004at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0019205; F:nucleobase-containing compound kinase activity; IEA:InterPro.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd01428; ADK; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   HAMAP; MF_00235; Adenylate_kinase_Adk; 1.
DR   InterPro; IPR000850; Adenylat/UMP-CMP_kin.
DR   InterPro; IPR033690; Adenylat_kinase_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR23359:SF70; ADENYLATE KINASE 1, ISOFORM B; 1.
DR   PANTHER; PTHR23359; NUCLEOTIDE KINASE; 1.
DR   Pfam; PF00406; ADK; 1.
DR   PRINTS; PR00094; ADENYLTKNASE.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00113; ADENYLATE_KINASE; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU003330};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003330}.
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..27
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   225 AA;  24458 MW;  E19D93742D7294E0 CRC64;
     MAMEHESKQK AAGGGTSPGT SAPQTPTAAG EIIRDSNVPI IWVLGGPGCG KGTQCEKIVA
     KYNFSHFSTG DLLRDEVASG SDQGKELQEM MKKGLLVSNE TVLKLLEAAM TKALGGTVGY
     LIDGYPREPA QGPEFEKFIA PVDIVLYFEC SNILGRVVNV FDGISVLVLE VKLLPNYSLH
     HQLNALYVER GLRRDRGLFL FFVDQFVEVL RDVLVLGFAI SQRVG
//