ID B0WIR6_CULQU Unreviewed; 397 AA.
AC B0WIR6;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 77.
DE SubName: Full=Biotin-protein ligase ligase {ECO:0000313|EMBL:EDS28643.1};
GN ORFNames=CpipJ_CPIJ007071 {ECO:0000313|EMBL:EDS28643.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS28643.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS28643.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the biotin--protein ligase family.
CC {ECO:0000256|ARBA:ARBA00009934}.
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DR EMBL; DS231951; EDS28643.1; -; Genomic_DNA.
DR RefSeq; XP_001848600.1; XM_001848548.1.
DR AlphaFoldDB; B0WIR6; -.
DR STRING; 7176.B0WIR6; -.
DR KEGG; cqu:CpipJ_CPIJ007071; -.
DR VEuPathDB; VectorBase:CPIJ007071; -.
DR VEuPathDB; VectorBase:CQUJHB003745; -.
DR eggNOG; KOG1536; Eukaryota.
DR HOGENOM; CLU_051096_2_1_1; -.
DR InParanoid; B0WIR6; -.
DR OMA; GHEENMS; -.
DR PhylomeDB; B0WIR6; -.
DR GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:InterPro.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd16442; BPL; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR InterPro; IPR003142; BPL_C.
DR InterPro; IPR004143; BPL_LPL_catalytic.
DR NCBIfam; TIGR00121; birA_ligase; 1.
DR PANTHER; PTHR12835; BIOTIN PROTEIN LIGASE; 1.
DR PANTHER; PTHR12835:SF5; BIOTIN--PROTEIN LIGASE; 1.
DR Pfam; PF02237; BPL_C; 1.
DR Pfam; PF03099; BPL_LplA_LipB; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:EDS28643.1}.
FT DOMAIN 132..320
FT /note="BPL/LPL catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51733"
SQ SEQUENCE 397 AA; 44546 MW; 26B4CA3E983FEBBD CRC64;
MKENNAFDER RSARSFSTTK RDGRIEFVPY EDNKQNLGIF KHVLSSELGI KFKTSHDHEA
SCYQSAFLIG SEEVKRSFLS DLSIPNELKV SDLTLQFCSK SDLIPAASES HLPVLTDQPP
EDFSTQFFND HLKTNKIGRL TLYLPLVTSS MIIVSNATLP HGFVAIPRRQ SRGTGRNRNQ
WLSPDGCAMF SLQLHVPLDS PLGQRLPMVQ HLVALGIVLG IRNQPGYGEL DVRLKWPNDV
YANGRSKLGG IIVNSQLEGS RAVVNVGCGV NLSNSTPTTC VNDVIGEFNR ERRERLRALG
YEQLLAQIFN EIERIFEEVQ RGKVEVLYDL YRRYWLHEGQ SVTIRDRDGL DVTGTVAGID
EYGYLLVKVD GAGQPICVHP DGNSFDMMKG LIIPKYC
//
