ID   B0WJ29_CULQU            Unreviewed;       519 AA.
AC   B0WJ29;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   SubName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase {ECO:0000313|EMBL:EDS28908.1, ECO:0000313|EnsemblMetazoa:CPIJ007158-PA};
GN   Name=6039035 {ECO:0000313|EnsemblMetazoa:CPIJ007158-PA};
GN   ORFNames=CpipJ_CPIJ007158 {ECO:0000313|EMBL:EDS28908.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS28908.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS28908.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ007158-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ007158-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   EMBL; DS231955; EDS28908.1; -; Genomic_DNA.
DR   RefSeq; XP_001848713.1; XM_001848661.1.
DR   AlphaFoldDB; B0WJ29; -.
DR   STRING; 7176.B0WJ29; -.
DR   EnsemblMetazoa; CPIJ007158-RA; CPIJ007158-PA; CPIJ007158.
DR   GeneID; 6039035; -.
DR   KEGG; cqu:CpipJ_CPIJ007158; -.
DR   VEuPathDB; VectorBase:CPIJ007158; -.
DR   VEuPathDB; VectorBase:CQUJHB000246; -.
DR   eggNOG; KOG2645; Eukaryota.
DR   HOGENOM; CLU_017594_1_2_1; -.
DR   InParanoid; B0WJ29; -.
DR   OMA; WETAVNQ; -.
DR   OrthoDB; 1366859at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd16018; Enpp; 1.
DR   Gene3D; 3.30.1360.180; -; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR002591; Phosphodiest/P_Trfase.
DR   PANTHER; PTHR10151:SF120; BIS(5'-ADENOSYL)-TRIPHOSPHATASE; 1.
DR   PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR   Pfam; PF01663; Phosphodiest; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           31..519
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011408115"
FT   TRANSMEM        454..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   519 AA;  59219 MW;  BC38197B856A9EF8 CRC64;
     MIPRSTARSR WLVVVAAVTL LHLLDGGAWC KRVRGNDPAD ETVLIVVSYD AFRTEYLRRG
     SASYMAELGH NGTWAEYLRN VFPTKTFPNH HSIATGVFPN QHGVMANGLY DHGRGKINYS
     YDLFHFNEEL VPIWTLNEQH GGHSGCMMWP GSDFPYTRGN ITCSHLQPFN LTLPWNDRVD
     TAFRWIRDPT RPANLVMLYI EEPDYYGHIY SPESDRVAQL VVKLNDLTRY IHDKIREFGL
     VERVNVLHLS DHGMDSLMPK NFINLTSFVP ADMKFDVYGS TPVLQVVPKV KQQTADLYRA
     LKNASEKSGN FDVYTLENLP TRWHFNNSQR TGPITAVAKL GYGFDDMWDT VEYYRKAFNV
     SVTSETKYGV HGYDNELPIM HPIFFGYGPR IRERTTVEPF DTVDLYYLFC ELLGLDAPYY
     LDGKREHIVA VLRNDSRDDD DDDPSGTSAR TVTLMVIFAG SLLASFGLVS MLAYVVIWRR
     RRRENLVPHY LYDETESFSG RSQQAAAGRR SPTATAAAT
//