ID B0WJC7_CULQU Unreviewed; 339 AA.
AC B0WJC7;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Lipase {ECO:0000313|EMBL:EDS29101.1, ECO:0000313|EnsemblMetazoa:CPIJ007363-PA};
GN Name=6039205 {ECO:0000313|EnsemblMetazoa:CPIJ007363-PA};
GN ORFNames=CpipJ_CPIJ007363 {ECO:0000313|EMBL:EDS29101.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS29101.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS29101.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ007363-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ007363-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|RuleBase:RU004262}.
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DR EMBL; DS231959; EDS29101.1; -; Genomic_DNA.
DR RefSeq; XP_001848811.1; XM_001848759.1.
DR AlphaFoldDB; B0WJC7; -.
DR EnsemblMetazoa; CPIJ007363-RA; CPIJ007363-PA; CPIJ007363.
DR KEGG; cqu:CpipJ_CPIJ007363; -.
DR VEuPathDB; VectorBase:CPIJ007363; -.
DR VEuPathDB; VectorBase:CQUJHB001314; -.
DR eggNOG; ENOG502RYX8; Eukaryota.
DR HOGENOM; CLU_027171_2_3_1; -.
DR InParanoid; B0WJC7; -.
DR OMA; NVNRTWV; -.
DR OrthoDB; 3599192at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013818; Lipase.
DR InterPro; IPR000734; TAG_lipase.
DR PANTHER; PTHR11610; LIPASE; 1.
DR PANTHER; PTHR11610:SF186; LIPASE H-RELATED; 1.
DR Pfam; PF00151; Lipase; 1.
DR PRINTS; PR00821; TAGLIPASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 78..332
FT /note="Lipase"
FT /evidence="ECO:0000259|Pfam:PF00151"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 339 AA; 37564 MW; 727ED8CD8AB55507 CRC64;
MGSRDASLGE MGGQNSQPSS IKSNTTNGER SVASQALDQD ELLANRLGIV VGALGNTFSQ
IFFGPNELRS EVTFWCANPN HYDYMQVTIN DQDVQYKLDV SKPLLFLTHG WTDNVNRTWV
KDIVGDYVTY IGGNICAVDW SRLALVEYNL AARNTPKVGR YLAKFVKFLL KQGFSMDQLT
LVGHSMGAHI SGIAGAALDG AVPMIVGLDP AGPSFTRPFL VSTDRRLDKS DALFVQAVHT
DKNIIGTSTN VGHQDFYTNN GASPQPGCEF PLVNNDTTKA YLQFICSHFK AVEYFRASLN
PQHIFEGTNC HSYFYYRRGE CSNNTRADFG LYNKFVSMR
//
