ID B0WMQ1_CULQU Unreviewed; 1222 AA.
AC B0WMQ1;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 82.
DE RecName: Full=Transcription initiation factor TFIID subunit 2 {ECO:0000256|ARBA:ARBA00017363};
DE AltName: Full=Transcription initiation factor TFIID 150 kDa subunit {ECO:0000256|ARBA:ARBA00033345};
GN Name=6040602 {ECO:0000313|EnsemblMetazoa:CPIJ008434-PA};
GN ORFNames=CpipJ_CPIJ008434 {ECO:0000313|EMBL:EDS31136.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS31136.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS31136.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ008434-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ008434-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF2 family.
CC {ECO:0000256|ARBA:ARBA00010937}.
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DR EMBL; DS232000; EDS31136.1; -; Genomic_DNA.
DR RefSeq; XP_001849978.1; XM_001849926.1.
DR AlphaFoldDB; B0WMQ1; -.
DR STRING; 7176.B0WMQ1; -.
DR MEROPS; M01.972; -.
DR EnsemblMetazoa; CPIJ008434-RA; CPIJ008434-PA; CPIJ008434.
DR KEGG; cqu:CpipJ_CPIJ008434; -.
DR VEuPathDB; VectorBase:CPIJ008434; -.
DR VEuPathDB; VectorBase:CQUJHB013880; -.
DR eggNOG; KOG1932; Eukaryota.
DR HOGENOM; CLU_002317_0_0_1; -.
DR InParanoid; B0WMQ1; -.
DR OMA; QYMAAQR; -.
DR OrthoDB; 11119at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09839; M1_like_TAF2; 1.
DR Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR Gene3D; 2.60.40.1730; tricorn interacting facor f3 domain; 1.
DR InterPro; IPR042097; Aminopeptidase_N-like_N_sf.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014782; Peptidase_M1_dom.
DR InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR InterPro; IPR037813; TAF2.
DR PANTHER; PTHR15137; TRANSCRIPTION INITIATION FACTOR TFIID; 1.
DR PANTHER; PTHR15137:SF9; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2; 1.
DR Pfam; PF01433; Peptidase_M1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF63737; Leukotriene A4 hydrolase N-terminal domain; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 263..513
FT /note="Peptidase M1 membrane alanine aminopeptidase"
FT /evidence="ECO:0000259|Pfam:PF01433"
FT REGION 1075..1222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1092..1144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1148..1171
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1172..1195
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1197..1222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1222 AA; 139128 MW; 29C0AF60364771AF CRC64;
MKKEKTADNI LSLTGISFER KSIIGFVELT IVPVKETLKI IRLNCRQCRI YRVILNDSYE
ATFHYFDPFL DICQENKTKS LEVFSKCHLE MAKKTDPDNN AGELVIVVPE QATHLIGEGR
GLRIGIEFSL EDPSGGVHFV IPEGEGTMEE RAAHMFTYGH ENSSRLWFPC VDSYAEPCTW
KLEFTVDKNM TAVSCGELVE VVMTPDLRRK TYHYTVSVPV SAPNIALAVG PFEIYVDPHM
HEVTHFCLPQ LMPLLKNTVR YMHEAFEFYE EALTQRYPFT CYKQVFVDEI DNDCNAYATM
TILSTHLLHS IAIIDQTFVA RKVMSKAIAE QFFGCFITMQ NWSDAWLARG IAEYMCGLYS
KKCFGNNAYR AWIRDELAEV VKYEEKFGGI ILDCSQAPAP PAVSSINQSP AAPAKAYNDN
PFYFPIKNIH TISPKYVEIM RKKAHLVIRM LEHRIGQELL LQVFNKQLAL ASNAASTKIS
SGLWHQLHIS TNIFTKAIFT VTGKDMAVFI DQWVRTGGHA RFTMTSVFNR KRNTIELEIR
QDAVNQKGVR KYVGPLLIQL QELDGTFKHT LQIENIVVKS DITCHSKSRR NKKKKIPLCT
GEEVDMDLSP MDESPVLWIR LDPEMTLLRS VHIEQPDFQW QFQLRHERDV TAQLDSIAAL
ERYASPATRL ALTDTIENEQ IFYEVRCKAA LCLTKVANSM VTSWQGPPAM LTIFKKFFGS
FSAPHIIRQN NFTNFQHYFL QKTIPVAMAG LRTAHGICPP EVIRFLLDLF KYNDNTKNHY
SDNYYRAALV EALGNSITPV VSMVHQGMAL TSENLSADSK LVLEEVTRIL NLEKHLPSYK
YTVSIACLKV IRKLQKCGHL PTNPKIYRSY AEYGQYIDVR VAAMECLVDY VKIDGRWEDL
ENLIDLLETD PDPMARHRLG RLLIENLPFD KGNRHRLDRE ELALRIWNNM NGLLSHDTRL
RCDMVDLYYT LYGTRVPNCL PNPELASILK PQNWPRHLPP PLDVKPLDLI DIGPTELLIP
PIRSREASPL GIGEEEIRDE IILETVDSNI KTEIVEMVDR QSDLKEEIVD LDDQNSITMV
STEPPPVKKS KTDFYSDNSI SLPGITPSSS SVTGPTGFEP GMFGSSKSSE TVVPTVGSEP
SVSSKSDGSK KKKKKDKKKH KHKHKHKHNK DKDRDREKDR EKSKEKKDPS IVRLIKEDTQ
ETLSSADSSS RDSNPTTLDL TL
//
