ID   B0WN55_CULQU            Unreviewed;       736 AA.
AC   B0WN55;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   24-JAN-2024, entry version 78.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 25 homolog {ECO:0000256|ARBA:ARBA00024421};
DE   AltName: Full=UTP25 small subunit processor component {ECO:0000256|ARBA:ARBA00032325};
GN   Name=6040800 {ECO:0000313|EnsemblMetazoa:CPIJ008493-PA};
GN   ORFNames=CpipJ_CPIJ008493 {ECO:0000313|EMBL:EDS31486.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS31486.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS31486.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ008493-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ008493-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the UTP25 family.
CC       {ECO:0000256|ARBA:ARBA00009223}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS232007; EDS31486.1; -; Genomic_DNA.
DR   RefSeq; XP_001850139.1; XM_001850087.1.
DR   AlphaFoldDB; B0WN55; -.
DR   STRING; 7176.B0WN55; -.
DR   EnsemblMetazoa; CPIJ008493-RA; CPIJ008493-PA; CPIJ008493.
DR   GeneID; 6040800; -.
DR   KEGG; cqu:CpipJ_CPIJ008493; -.
DR   VEuPathDB; VectorBase:CPIJ008493; -.
DR   VEuPathDB; VectorBase:CQUJHB015953; -.
DR   eggNOG; KOG2340; Eukaryota.
DR   HOGENOM; CLU_018705_1_0_1; -.
DR   InParanoid; B0WN55; -.
DR   OMA; KYFRQTI; -.
DR   OrthoDB; 5473087at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010678; UTP25.
DR   PANTHER; PTHR12933; ORF PROTEIN-RELATED; 1.
DR   PANTHER; PTHR12933:SF0; U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG; 1.
DR   Pfam; PF06862; UTP25; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT   REGION          1..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..54
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..96
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        97..151
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   736 AA;  84745 MW;  2E8A6B72522150E1 CRC64;
     MKKQQRKERA QRAPVSRFRK NLRHMERSKE AMEALRRQQD AEVKYKRKMN GAVEEEQELA
     AMGSDGEEAG EDDHFDVLVK TLNSGRKGAD RREAAIESDE SEEEEEEEDE QSAEVEEEED
     EEMDDGSEVE EESSGEEGEE EEEDEEEKDE ESDPYLNHIS YNISPQMLES VSANPAVTNK
     STIAFGRLGQ LMVEIPKDRS KEAKGATLLD DDEKYAPEGT VPKALNPEKL DVKKLFIKEK
     IQRNLEDPVF NKLQAECFSI LNNYQDLYFP GRNLDNGSDL QMVYCLHALN HILKSTSKIL
     HHNLKLAEAK GKKKKKVATV LEYRDQGLVR PKVLIVVPFR SAALKIVDTI QRLFTGDDPK
     LVTNYKRFQS EYGGETLAFP KVNPKPEDYE RTFAGNTDDN FRIGISFSKS SMKLYTKYYN
     SDLILASPLG LRMTIGAEGE SERDFDFLSS IELLILDQAE ICLVQNWDHV LHLMDHLHLQ
     PQSTEHTDFS RVRYWCLNGW SRFYRQTLLL SSHDLPEFRS IFNNKCANYH GKARVANPVK
     TGSIRHAIVS LPQTFHRIEV PSLEASYDAK FAHFTTVLLP QLRSVTMART LIFIPSYFDY
     VRLRNYFKKE ELNFVQICEY SKDGKIARAR DMFFHGSAHF MLYSERSHFF RRTRIKGIRH
     LVFYQLPQFP QFYPEMINLM ADEYQNKHDG VDASSMTVTA LYTKYDLLRL SAVIGTQQAA
     KLAGSARAAH TFTTQK
//