ID   B0WNQ5_CULQU            Unreviewed;       816 AA.
AC   B0WNQ5;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   24-JAN-2024, entry version 79.
DE   SubName: Full=Hook protein {ECO:0000313|EMBL:EDS31896.1};
GN   Name=6041028 {ECO:0000313|EnsemblMetazoa:CPIJ008597-PA};
GN   ORFNames=CpipJ_CPIJ008597 {ECO:0000313|EMBL:EDS31896.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS31896.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS31896.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ008597-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ008597-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
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DR   EMBL; DS232014; EDS31896.1; -; Genomic_DNA.
DR   RefSeq; XP_001850339.1; XM_001850287.1.
DR   AlphaFoldDB; B0WNQ5; -.
DR   STRING; 7176.B0WNQ5; -.
DR   EnsemblMetazoa; CPIJ008597-RA; CPIJ008597-PA; CPIJ008597.
DR   KEGG; cqu:CpipJ_CPIJ008597; -.
DR   VEuPathDB; VectorBase:CPIJ008597; -.
DR   VEuPathDB; VectorBase:CQUJHB012727; -.
DR   eggNOG; KOG4643; Eukaryota.
DR   HOGENOM; CLU_346222_0_0_1; -.
DR   InParanoid; B0WNQ5; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; IEA:InterPro.
DR   Gene3D; 6.10.250.1080; -; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR043936; HOOK_N.
DR   PANTHER; PTHR18947:SF28; GIRDIN, ISOFORM A; 1.
DR   PANTHER; PTHR18947; HOOK PROTEINS; 1.
DR   Pfam; PF19047; HOOK_N; 1.
DR   SUPFAM; SSF116907; Hook domain; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           29..816
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011408303"
FT   DOMAIN          107..193
FT                   /note="HOOK N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19047"
FT   REGION          703..816
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          250..422
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        704..731
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        732..746
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        747..771
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   816 AA;  93670 MW;  B04979A1A8612BAF CRC64;
     MRPWREGVTK HVVTTIIIII LQTHLTQSNG TNNLSQVAPT SNNPSTFGID LSDVQYQLSG
     PPAIFCKRRG ILSGKHGTAL HSVYLQIDPT PRYHLDEVVR SSRQHRALHN FTAVVNNLIS
     LYVDNFNQTV LYLPDCAILS EQPASHKGIE QMKLLITLLL GAAVQCSNQE KLIKRIQSLN
     EAAQTSIMTV IREVIEGQSL VLNQPAMENL SLDANGKHVV RLVEERDHYW ALWTRSEKSA
     VEAAIDTAEI GRLTASLAAS KDQINKLRQE GDEAAELLRK LKTEFECKNK QYQELSVKSQ
     DWYSKAQRVS AYRDEADALR ERAERAEYAE KELRSLRPKL DKLDFYCNRV NQLEEDKSAL
     EETKKLVEGQ LDRLQQRHEQ LSEMEAETER YRHEITNMSQ MLATANNQIE ELIEENAALQ
     LSVPSSTVEK VDFNEHQPSA RYSLSDQLTS HVKSKNIKLE LENRRLQADL ECLKQSPSKS
     SAKDLQFEER LKTLKMDNSQ LASSRNSLQR QLELIKQDHE TLQRLHAQLN DDKAMLGSSV
     EELKVYNRSL KDHVQKQSNE MNLMEQKMAT LAVEHSELQD DFQQIFQEND QLKSTNNSLV
     RQMVDLEVEL KHKLERIAVL ETEYASVNQR CEMLYSMNTR LDNEKRAERE QYSNLLNQYN
     QHMADSLDDT KHFHENEKMY MEKINELQRL KEKLEEKILA FYGKGNNSTP SKKNKKNPLS
     AFTFSNLRKN LMKSTPEKEK PKATGQSDKE TATPDAGSIE SDASSEEVFL NQLPSEREDS
     DFEGDYVNLR NYGARRSLMP EHKFQPKKPA RSSLPG
//