ID B0WP93_CULQU Unreviewed; 655 AA.
AC B0WP93;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Heat shock 70 kDa protein cognate 4 {ECO:0000313|EMBL:EDS32138.1, ECO:0000313|EnsemblMetazoa:CPIJ008915-PA};
GN Name=6041235 {ECO:0000313|EnsemblMetazoa:CPIJ008915-PA};
GN ORFNames=CpipJ_CPIJ008915 {ECO:0000313|EMBL:EDS32138.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS32138.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS32138.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ008915-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ008915-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
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DR EMBL; DS232020; EDS32138.1; -; Genomic_DNA.
DR RefSeq; XP_001850527.1; XM_001850475.1.
DR AlphaFoldDB; B0WP93; -.
DR STRING; 7176.B0WP93; -.
DR EnsemblMetazoa; CPIJ008915-RA; CPIJ008915-PA; CPIJ008915.
DR GeneID; 6041235; -.
DR KEGG; cqu:CpipJ_CPIJ008915; -.
DR VEuPathDB; VectorBase:CPIJ008915; -.
DR VEuPathDB; VectorBase:CQUJHB018229; -.
DR eggNOG; KOG0101; Eukaryota.
DR HOGENOM; CLU_005965_3_0_1; -.
DR InParanoid; B0WP93; -.
DR OMA; KANPIMM; -.
DR OrthoDB; 143at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR CDD; cd10233; HSPA1-2_6-8-like_NBD; 1.
DR Gene3D; 1.20.1270.10; -; 1.
DR Gene3D; 3.30.30.30; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR029048; HSP70_C_sf.
DR InterPro; IPR029047; HSP70_peptide-bd_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR PANTHER; PTHR19375:SF395; HEAT SHOCK 70 KDA PROTEIN COGNATE 1-RELATED; 1.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR Pfam; PF00012; HSP70; 1.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 1.
DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR PROSITE; PS00297; HSP70_1; 1.
DR PROSITE; PS00329; HSP70_2; 1.
DR PROSITE; PS01036; HSP70_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003322};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Stress response {ECO:0000313|EMBL:EDS32138.1}.
FT REGION 616..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 655 AA; 71433 MW; F37170AA294138EC CRC64;
MAAAKAPAVG IDLGTTYSCV GVFQHGKVEI IANDQGNRTT PSYVAFTDTE RLIGDAAKNQ
VAMNPCNTIF DAKRLIGRKF DEQNVQADMK HWPFTVVSIE GKPKIQVEYK GETKSFFPEE
ISSMVLTKMK ETAEAYLGKT VTNAVVTVPA YFNDSQRQAT KDAGTIAGLN VLRIINEPTA
AAIAYGLDKK TAGERNVLIF DLGGGTFDVS ILSIDDGIFE VKSTAGDTHL GGEDFDNRLV
NHFATEFKRK HKKDLSTNKR ALRRLRTACE RAKRTLSSST QASIEIDSLF EGTDFYTSIT
RARFEELNAD LFRSTMEPVE KAIRDAKMDK ASIHDIVLVG GSTRIPKVQK LLQDFFNGKE
LNKSINPDEA VAYGAAVQAA ILHGDKSEEV QDLLLLDVTP LSLGIETAGG VMSVLIKRNT
TIPTKQTQTF TTYSDNQPGV LIQVFEGERA MTKDNNLLGK FELSGIPPAP RGVPQIEVTF
DIDANGILNV TALEKSTNKE NKITITNDKG RLSKEDIERM VNEAEKYRNE DDKQKECISA
KNGLESYCFN MKATMEDDKL KDKITDSDKT LILDKCNDTI KWLDANQLAD KEEYEHRQKE
LESVCNPIIT KLYQSAGGAP PGGMPGFPGG APGAGAGGAA PGAGTGSGPT IEEVD
//
