ID B0WSD3_CULQU Unreviewed; 1655 AA.
AC B0WSD3;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|EMBL:EDS33778.1, ECO:0000313|EnsemblMetazoa:CPIJ010068-PA};
GN Name=6042514 {ECO:0000313|EnsemblMetazoa:CPIJ010068-PA};
GN ORFNames=CpipJ_CPIJ010068 {ECO:0000313|EMBL:EDS33778.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS33778.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS33778.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ010068-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ010068-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS232069; EDS33778.1; -; Genomic_DNA.
DR RefSeq; XP_001851807.1; XM_001851756.1.
DR STRING; 7176.B0WSD3; -.
DR EnsemblMetazoa; CPIJ010068-RA; CPIJ010068-PA; CPIJ010068.
DR GeneID; 6042514; -.
DR KEGG; cqu:CpipJ_CPIJ010068; -.
DR VEuPathDB; VectorBase:CPIJ010068; -.
DR VEuPathDB; VectorBase:CQUJHB005257; -.
DR eggNOG; KOG0059; Eukaryota.
DR HOGENOM; CLU_000604_19_1_1; -.
DR InParanoid; B0WSD3; -.
DR OMA; QIMGICP; -.
DR OrthoDB; 773084at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF250; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 3; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:EDS33778.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 884..905
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1055..1075
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1105..1122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1134..1156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1168..1188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1200..1217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1268..1290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 514..744
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1335..1565
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1655 AA; 186646 MW; 02A0A34E5ED970D2 CRC64;
MTSSGWGKFV LLLWKNWIIS KRHYFQTFFE ILIPVVACLL LILVRGLVDP KEYKEDFIFR
PLDLNSIAHL RTLNLPIQLM IAFSPRNSLL EQIITASIGI LNGPHLQPMP FDNASTMQNF
LQNNNYLVGV EFPDSYANIT TLPNHVEFAL RYPAEMRTFV AVGTEFWNNW QTNRLFPAFD
VPGLRNPTSE DGGYPANYYW ETFASIQSAV SQAIVVEKSP DHRLSGIFLR RYPYPAFYSD
PLLLGLENLL PLIIVVAFFY TCINTVKYIA VEKERQLKEA MKIMGLPSWL HWMAWFVKTQ
IMLLVAISLI TILLCVSMTT NTDLAVFTFA DWSVVWVYLL VYSVVTIMFC FMMSTFFSKA
NTASGIAGLM WFVFVMPYNI AFANYDTMSL GAKLALCLFH NSGMSFGFML MMRHEGTTTG
VQWSNLFSPV TADDDLSVGA TMMMLLAAGV IYLLIALYVE KVMPGEFGVA EPWYFPFTKK
FWTNKVDVIE DVNDVMLDNP NSRESDPTGK HAGIQIKGLR KVFDKSKVTV KGTYLNMFDD
QITVLLGHNG AGKTTTMSML TGMFSPTSGT AMINDCDIRT NMDGARQSLG LCPQHNVLFD
EMTVGEHIQF FARLKGVERK DIPSEVRHYV KILELEDKIH SQSSTLSGGM KRKLAVGVAL
CGGSKVVLCD EPTSGMDPAA RRALWDLLIM EKKGRTILLS THFMDEADIL GDRIAIMADG
ELKAVGSSFF LKKKFGVGYR LICVKGDACN PSAVTELLQR YIPDIQVETD IGTELSYVLN
ENYTSVFQIM LQELEENSQR LQLDSYGVSL TTLEEVFLKV GSDSFGVDTH EHDTNGHLDT
NDRTASNVTL DLQESEKLLT GFPLKMNQIR AMFMKKLIVT YRSWISMAVQ IFIPIFFVVM
TMVIVRSFPD NVQLPTLWMN FDDYVRTTTV LEANTENAEL VSAYQGLFQS TGPDQQLITI
MEPMNDYILR RTIENTPLVT NEFMVGATLK SDNVTVWFNT QGFHTASLSI ATFYNAFVRT
VCSDCSIKIA NKPLPFRPET RFSQLQAGNN MGFQLAFNTG FAMAFVAALY VMFYIKERVT
RAKLLQFVSG VNVFAFWAVS FLWDYITYIV TILFYIATLA AFQEDGWSSG EELGRVFLIL
LVFGFAFLPL TYLLSFRFDV PASGFVKLML LNIFTGIIFF MAVFLLLFDG FDLQDVGRGL
EWGFMIFPLF ALSHALSNIN IASTTLRICD SQCELIPECT EELLCKLFPN CCNVKIFSFE
PTGINRNLLF MSGLGAACFV ILMIIEYRVM QRIFTSLMRK RSPPVLNPAL IDSDVLAEKE
RIRVMSMGEI SATSLVLRDV TKFYKSFLAV NQMSVSVEHS QCFGLLGVNG AGKTSTFKML
TGDEDISSGD AWVNGTSLRT DMTTVHQQIG YCPQFDALID DLTGRETLMI FALLRGIPKD
EVSMVGLRLA EDLNFMKHID KRTKQYSGGN KRKLSTALAL MGRPTVVYLD EPTTGMDPGA
KRQLWDVVCK ERSAGKSIVL TSHSMEECEA LCTKLAIMVN GEFKCIGSTQ HLKNKFSNGY
YLTVKLKKKT TESGPEKVAE IKNYIVAKIP EAELKEEYME SLTYQIPKTD IRWSTMFGIM
EQAKQELDIE DYVLGQTSLE QVFLSFTKYQ RVEDS
//
