ID   B0X055_CULQU            Unreviewed;       631 AA.
AC   B0X055;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   24-JAN-2024, entry version 79.
DE   RecName: Full=DIRP domain-containing protein {ECO:0000259|SMART:SM01135};
GN   Name=6045718 {ECO:0000313|EnsemblMetazoa:CPIJ012736-PA};
GN   ORFNames=CpipJ_CPIJ012736 {ECO:0000313|EMBL:EDS37930.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS37930.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS37930.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ012736-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ012736-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the lin-9 family.
CC       {ECO:0000256|ARBA:ARBA00006732}.
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DR   EMBL; DS232229; EDS37930.1; -; Genomic_DNA.
DR   RefSeq; XP_001863027.1; XM_001862992.1.
DR   AlphaFoldDB; B0X055; -.
DR   STRING; 7176.B0X055; -.
DR   EnsemblMetazoa; CPIJ012736-RA; CPIJ012736-PA; CPIJ012736.
DR   GeneID; 6045718; -.
DR   KEGG; cqu:CpipJ_CPIJ012736; -.
DR   VEuPathDB; VectorBase:CPIJ012736; -.
DR   VEuPathDB; VectorBase:CQUJHB006128; -.
DR   eggNOG; KOG1019; Eukaryota.
DR   HOGENOM; CLU_013763_1_0_1; -.
DR   InParanoid; B0X055; -.
DR   OMA; FEEERMY; -.
DR   OrthoDB; 180996at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0017053; C:transcription repressor complex; IEA:InterPro.
DR   GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR   InterPro; IPR033471; DIRP.
DR   InterPro; IPR010561; LIN-9/ALY1.
DR   InterPro; IPR045831; LIN9_C.
DR   PANTHER; PTHR21689; LIN-9; 1.
DR   PANTHER; PTHR21689:SF2; PROTEIN LIN-9 HOMOLOG; 1.
DR   Pfam; PF06584; DIRP; 1.
DR   Pfam; PF19438; LIN9_C; 1.
DR   SMART; SM01135; DIRP; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT   DOMAIN          207..312
FT                   /note="DIRP"
FT                   /evidence="ECO:0000259|SMART:SM01135"
FT   REGION          1..78
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          98..164
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          608..631
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..33
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        139..159
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        613..631
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   631 AA;  70392 MW;  5B09C245BB7E9021 CRC64;
     MSSLEEQDEG GGRTRETTPE PDETLRIKDE PMDDDGEDGS PPPAFGPAAL GLHPVGAAFP
     TRTTPRQEPV QVLNARGMPA RIRKKNKLFF DDELLVNDRI PPKGSPKKGG GSVPASPQKG
     LVTPGKTLTR SGQKRKTLSR YVKMKDSLKK RKEDPDEEEG AVPTGSATKV INPIALLDKK
     ASQRIGLRLR NLLKLPKAHK FVSYEWFYSN IDRALFEGEN DFQLCMREMY PDLKTRHLTR
     AEWNHIRKTM GKPRRCSVAF FAEERRELER KRQKIRLLQT KRSGDVSFVR DLPKEIPQPL
     SVGTKVTARL RAPQDGLFTG TVEAIDVIAS SYRVSFDRPG LGSHTIPDFE VVANDTLDKI
     ALNSITKDFR PKYQNASFYV ASPAVKNPIT GIKGDPLLGG DSYPKISGDN KMLFPKDNIG
     GFPVKLLELI VRTKKTLSAK QMKLLRLQNM NSEAEIYKSY GDPFPEEFQK RYASLVVAME
     KLNRDILEQL NQLQSSTRNL TQDPSVMAMI APSHLREQCR EQAEETFDKN NNGQLTNDSM
     IKLIKDLTTI MYVASNLGTA DTEQSLEVLR GCMEETKGRL DFDNMASFQR GVHQHMKHIQ
     VGFAAAAAAA ASSKPEPSSS QPKKKVASAG N
//