ID B0X1H0_CULQU Unreviewed; 784 AA.
AC B0X1H0;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 88.
DE SubName: Full=Glycogen debranching enzyme {ECO:0000313|EMBL:EDS38597.1, ECO:0000313|EnsemblMetazoa:CPIJ013040-PA};
GN Name=6046268 {ECO:0000313|EnsemblMetazoa:CPIJ013040-PA};
GN ORFNames=CpipJ_CPIJ013040 {ECO:0000313|EMBL:EDS38597.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS38597.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS38597.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ013040-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ013040-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; DS232259; EDS38597.1; -; Genomic_DNA.
DR RefSeq; XP_001863470.1; XM_001863435.1.
DR AlphaFoldDB; B0X1H0; -.
DR STRING; 7176.B0X1H0; -.
DR EnsemblMetazoa; CPIJ013040-RA; CPIJ013040-PA; CPIJ013040.
DR KEGG; cqu:CpipJ_CPIJ013040; -.
DR VEuPathDB; VectorBase:CPIJ013040; -.
DR VEuPathDB; VectorBase:CQUJHB008313; -.
DR eggNOG; KOG3625; Eukaryota.
DR HOGENOM; CLU_001517_1_0_1; -.
DR InParanoid; B0X1H0; -.
DR OMA; WENINEL; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0004134; F:4-alpha-glucanotransferase activity; IEA:InterPro.
DR GO; GO:0004135; F:amylo-alpha-1,6-glucosidase activity; IEA:InterPro.
DR GO; GO:0005980; P:glycogen catabolic process; IEA:InterPro.
DR CDD; cd11327; AmyAc_Glg_debranch_2; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR InterPro; IPR010401; AGL/Gdb1.
DR InterPro; IPR032788; AGL_central.
DR InterPro; IPR029436; AGL_euk_N.
DR InterPro; IPR032792; AGL_glucanoTrfase.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10569; GLYCOGEN DEBRANCHING ENZYME; 1.
DR PANTHER; PTHR10569:SF2; GLYCOGEN DEBRANCHING ENZYME; 1.
DR Pfam; PF14701; hDGE_amylase; 1.
DR Pfam; PF14702; hGDE_central; 1.
DR Pfam; PF14699; hGDE_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 38..113
FT /note="Eukaryotic glycogen debranching enzyme N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14699"
FT DOMAIN 121..559
FT /note="Glycogen debranching enzyme glucanotransferase"
FT /evidence="ECO:0000259|Pfam:PF14701"
FT DOMAIN 697..783
FT /note="Glycogen debranching enzyme central"
FT /evidence="ECO:0000259|Pfam:PF14702"
SQ SEQUENCE 784 AA; 88815 MW; 7E5674A72F616D31 CRC64;
MHQVPDEHAL PLHLHLTLAL SQYEQHYHAF MEQNHCIGKD FNRHVYTQLQ WCSPTGTVLS
PSGGSKFVSI RDVDCYCTVH LNHSGAYHFY VQYEGVEGPQ AGLYVQVEPN LTVGKGDSLT
VLPLEAIRCQ TVIAKLMGPV GSWEAKLRVA KESGYNVIHF TPIQELGGSR SAYSLKNQLK
VNPDFANDKD HAVGFEDVEG VVKKMRQEWG MASICDIVLN HTANESIWIR EYAECSYNCF
TCPHLRPAFL LDAMLARVGE DVAAGLLEHV GIPSVVETAN HLDALRWQVH TNYLPQIKLH
ELFQCNIEKY MARFSEQASK QSPTAAQDVP EGDLQLKHDP EYRRLGAEID FDRAMRTYNV
FRKDCFDEDS RKRKCVEAFR AKLQWLNEEV RKEIQGHLDY AIENCLAGTR YERVQADGPQ
VKGISIKYPL FMKYFTQYGV QGKSLKDIEE MMYGGPGKLF MAHNGWVINS DPLKDFARPQ
EGTGNVYIRR ELIAWGDSIK LRYGDKPEDS PYLWKHMKEY VDTTARIFDG VRLDNCHSTP
LHVAEWLLDS ARKVNPELYV VAELFTNSDY TDNIFVNRLG ITSLIREALS AWDSHEQGRL
VHRYGGAPVG AFFPCPKRIL APSIAHALFM DLTHDNPSPV EKRTIFDLIP SAALVSMACC
ATGSNRGYDE MVPHHIHVVD EERQYQEWGK HVDKTTGIVA VKEALNLLHG GLATRGFDQL
FVDQMNPDIV AVTRHSSQNH ETVILVAHTA FGYPSPWAGP TGVRPLRFEG NLLEIVFEVQ
IYKK
//
