ID   B0X2T0_CULQU            Unreviewed;       526 AA.
AC   B0X2T0;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   24-JAN-2024, entry version 83.
DE   RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
GN   Name=6046811 {ECO:0000313|EnsemblMetazoa:CPIJ013580-PA};
GN   ORFNames=CpipJ_CPIJ013580 {ECO:0000313|EMBL:EDS39404.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS39404.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS39404.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ013580-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ013580-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
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DR   EMBL; DS232298; EDS39404.1; -; Genomic_DNA.
DR   RefSeq; XP_001863952.1; XM_001863917.1.
DR   AlphaFoldDB; B0X2T0; -.
DR   STRING; 7176.B0X2T0; -.
DR   EnsemblMetazoa; CPIJ013580-RA; CPIJ013580-PA; CPIJ013580.
DR   KEGG; cqu:CpipJ_CPIJ013580; -.
DR   VEuPathDB; VectorBase:CPIJ013580; -.
DR   VEuPathDB; VectorBase:CQUJHB012766; -.
DR   eggNOG; KOG2084; Eukaryota.
DR   HOGENOM; CLU_024539_1_0_1; -.
DR   InParanoid; B0X2T0; -.
DR   OMA; GGKLFWC; -.
DR   OrthoDB; 3024214at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   CDD; cd20071; SET_SMYD; 1.
DR   Gene3D; 1.10.220.160; -; 1.
DR   Gene3D; 6.10.140.2220; -; 1.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR46455; SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A; 1.
DR   PANTHER; PTHR46455:SF5; SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A; 1.
DR   Pfam; PF00856; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT   DOMAIN          44..287
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   REGION          1..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..40
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   526 AA;  59813 MW;  FEE6195194FCF0A9 CRC64;
     MLDLKQRKQK NQHQPHGSDE PQESIGDNGE TGQKSPPEEE LNNNKPYVVR HSDVWGRYLI
     ASRNLKAGEV IIQVEPLAVG PWAESDPVCL GCHRTFEVGA KTVRCPTCNW RICSPTCTGL
     TTHHSRLECI PLKEHGVAKL LETCSSATQI KLAYEAILAL RCLLLKRTAP DRYEKLLEMD
     AMNERRQQIT SLWKRNQEAI VQRIRDEWKF EEFSEAEVHT VCGIIEVNAF QIGPTEVHAR
     ALYPEAFYIM HDCTPNTTHT DQPGSHELTV RPTRDLKAGE PLTLSYSYTL QGTLKRRQHL
     CDSKFFWCQC PRCEDPTEFG THCSTLKCAK CPKGLVLSSN PLDQDAPWKC KNCPHTIPAQ
     SVTQLLNGLY KELESIGGNN VELFENFLLK YEPILHKNHY LFLSAKHSLC ELYGKAPNYL
     MHELTLDQIN RKEYLCRDLL TLADSYEPGL SRLRGQLMYE LQAPIMVKSR YLFETQSITL
     SQLKQTLKEV ARLLRQSAEI LGFEPPGSAD HEMAVAARNA LREMGG
//