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Database: UniProt
Entry: B0X2Z7_CULQU
LinkDB: B0X2Z7_CULQU
Original site: B0X2Z7_CULQU 
ID   B0X2Z7_CULQU            Unreviewed;       591 AA.
AC   B0X2Z7;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   20-JUN-2018, entry version 68.
DE   SubName: Full=Signal transduction protein lnk-realted {ECO:0000313|EMBL:EDS39499.1, ECO:0000313|VectorBase:CPIJ013686-PA};
GN   Name=6046891 {ECO:0000313|VectorBase:CPIJ013686-PA};
GN   ORFNames=CpipJ_CPIJ013686 {ECO:0000313|EMBL:EDS39499.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176 {ECO:0000313|Proteomes:UP000002320};
RN   [1] {ECO:0000313|EMBL:EDS39499.1, ECO:0000313|VectorBase:CPIJ013686-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS39499.1,
RC   ECO:0000313|VectorBase:CPIJ013686-PA};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000002320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|Proteomes:UP000002320};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J.,
RA   Mauceli E., Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L.,
RA   Amedeo P., Antoine C.H., Arensburger P., Bidwell S.L., Crawford M.,
RA   Camaro F., Devon K., Engels R., Hammond M., Howarth C., Koehrsen M.,
RA   Lawson D., Montgomery P., Nene V., Nusbaum C., Puiu D.,
RA   Romero-Severson J., Severson D.W., Shumway M., Sisk P., Stolte C.,
RA   Zeng Q., Eisenstadt E., Fraser-Liggett C.M., Strausberg R.,
RA   Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|VectorBase:CPIJ013686-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|VectorBase:CPIJ013686-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; DS232304; EDS39499.1; -; Genomic_DNA.
DR   RefSeq; XP_001864019.1; XM_001863984.1.
DR   ProteinModelPortal; B0X2Z7; -.
DR   STRING; 7176.CPIJ013686-PA; -.
DR   EnsemblMetazoa; CPIJ013686-RA; CPIJ013686-PA; CPIJ013686.
DR   GeneID; 6046891; -.
DR   KEGG; cqu:CpipJ_CPIJ013686; -.
DR   VectorBase; CPIJ013686-RA; CPIJ013686-PA; CPIJ013686.
DR   eggNOG; ENOG410IMWK; Eukaryota.
DR   eggNOG; ENOG41102PH; LUCA.
DR   HOGENOM; HOG000047355; -.
DR   InParanoid; B0X2Z7; -.
DR   OMA; YDTEFFR; -.
DR   OrthoDB; EOG091G0AQB; -.
DR   PhylomeDB; B0X2Z7; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   GO; GO:0035591; F:signaling adaptor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd10346; SH2_SH2B_family; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   Gene3D; 3.30.505.10; -; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR015012; Phe_ZIP.
DR   InterPro; IPR036290; Phe_ZIP_sf.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR030523; SH2B.
DR   InterPro; IPR035057; SH2B1_SH2.
DR   PANTHER; PTHR10872; PTHR10872; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF08916; Phe_ZIP; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF109805; SSF109805; 1.
DR   SUPFAM; SSF55550; SSF55550; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002320};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT   DOMAIN      205    315       PH. {ECO:0000259|PROSITE:PS50003}.
FT   DOMAIN      439    537       SH2. {ECO:0000259|PROSITE:PS50001}.
SQ   SEQUENCE   591 AA;  64023 MW;  2CE3C7A7E44041B8 CRC64;
     MANLTDGDQS FCSAGGGPVA TAPTTSTPTS ASGVAIGGAT STTGPTSAAA QTTTTASSGA
     TTGSGGVWAE FCERHARAAS ADFARSCVHY VTNNLPESAR QTVSHRDFMR RFIECFQEHF
     EHDFYRRRMQ SKTGNGTAMV LEESDYSEDT DSPKTNHKPF FRRLSFKGLR KGKVIHALFH
     KQHSDEVELS GSRASKTKLA KIVVECRKEG TVNYLTPESL EQPSNSHKWE KCKLVLVKTV
     GGYMLEFYSP PKSQKPRSGV FCFLITEARE TTALEMPDHE NTFVLKADNN MEYVIEARDT
     DDMRSWLATI RYCMRSTPTS QLPPISDLTG ANQSVTTPGQ GQGQGQHNNS TSISHGGGGG
     GGGGGGGLSS SLVNEVNNLT LNNQSALNAV PTMMAPELPP RRPDDRISSS SNFELTETDL
     EPAHETDTDL TAMMREYPWF HGTLARSEAA QLVLHNGISS HGVFLVRQSE TRKGEFVLTF
     NFQGKAKHLR MTLNDLGQCR VQHLWFPSIT EMLEHFRQHA IPLESGGTAD VTLTNFVVLP
     SHAMAAQHQQ QQSNSNNYST TTIGGAAGAT AGGTAGTASA NNPNTSPRHV R
//
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