ID B0X3M1_CULQU Unreviewed; 284 AA.
AC B0X3M1;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE RecName: Full=NR LBD domain-containing protein {ECO:0000259|PROSITE:PS51843};
GN Name=6047147 {ECO:0000313|EnsemblMetazoa:CPIJ013369-PA};
GN ORFNames=CpipJ_CPIJ013369 {ECO:0000313|EMBL:EDS39913.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS39913.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS39913.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ013369-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ013369-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS232317; EDS39913.1; -; Genomic_DNA.
DR RefSeq; XP_001864243.1; XM_001864208.1.
DR AlphaFoldDB; B0X3M1; -.
DR STRING; 7176.B0X3M1; -.
DR EnsemblMetazoa; CPIJ013369-RA; CPIJ013369-PA; CPIJ013369.
DR KEGG; cqu:CpipJ_CPIJ013369; -.
DR VEuPathDB; VectorBase:CPIJ013369; -.
DR VEuPathDB; VectorBase:CQUJHB005470; -.
DR eggNOG; KOG3575; Eukaryota.
DR HOGENOM; CLU_980910_0_0_1; -.
DR InParanoid; B0X3M1; -.
DR OrthoDB; 5400963at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR033544; NR0B1/2.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR PANTHER; PTHR24081:SF8; NR LBD DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24081; NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR PRINTS; PR01282; COUPTNFACTOR.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..162
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT REGION 219..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 284 AA; 31383 MW; 23F48C04664B2966 CRC64;
MCKNGVAGAE QLTFPLTAVL IMMRQHPRDQ KMPHHLTLSA IWLTFWHRFE TAYSRKNTMP
ARWCRTRVKR PAAECSAETF QKDACGLSDV AHIESLQEKS QCALEEYCRS QYPNQPTRFG
KLLLRLPSLR TVSSQVIEQL FFVRLVGKTP IETLIRDMLL SGTAQVAAAS SSSGLSPSPS
SYYNSCCSDV AAAALSSLMA STNQFTQFQS SLNFAAASSH NHNSNSNCSS STNNNNNNNN
VNSLDPLATL EGSSNTATSQ QAQDELDAEQ RQRQQQQQEQ LPAI
//
