ID B0X709_CULQU Unreviewed; 1324 AA.
AC B0X709;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Posterior sex combs protein {ECO:0000313|EMBL:EDS41703.1, ECO:0000313|EnsemblMetazoa:CPIJ015235-PA};
GN Name=6048528 {ECO:0000313|EnsemblMetazoa:CPIJ015235-PA};
GN ORFNames=CpipJ_CPIJ015235 {ECO:0000313|EMBL:EDS41703.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS41703.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS41703.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ015235-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ015235-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS232432; EDS41703.1; -; Genomic_DNA.
DR RefSeq; XP_001865431.1; XM_001865396.1.
DR STRING; 7176.B0X709; -.
DR EnsemblMetazoa; CPIJ015235-RA; CPIJ015235-PA; CPIJ015235.
DR GeneID; 6048528; -.
DR KEGG; cqu:CpipJ_CPIJ015235; -.
DR VEuPathDB; VectorBase:CPIJ015235; -.
DR VEuPathDB; VectorBase:CQUJHB000847; -.
DR eggNOG; KOG2660; Eukaryota.
DR HOGENOM; CLU_259612_0_0_1; -.
DR InParanoid; B0X709; -.
DR OMA; NFAQMGH; -.
DR OrthoDB; 460116at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR032443; RAWUL.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR10825:SF76; POLYCOMB GROUP PROTEIN PSC; 1.
DR PANTHER; PTHR10825; RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT; 1.
DR Pfam; PF16207; RAWUL; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 51..90
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 301..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 833..862
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..935
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 983..1020
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1035..1068
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1091..1173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1187..1248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..416
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 587..617
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..660
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..713
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..739
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 901..923
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1002..1020
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1035..1050
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1105..1159
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1209..1246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1324 AA; 145830 MW; 93FF91976F59C300 CRC64;
MVLLPAAKKS EMAGEGTNKV VAKKATVVNG PVSPYKPSKI HLSSVNPYIT CNLCKGYLID
ATTIVECLHS FCHSCIMKHL RTEQYCPQCE MMINKAKPNI KPDATLQAIV YKLVPGLYEK
ELLRKRAFYR QHPDQAALAT PEQRGEDTEH LIFGPSEKIS LSLEYAEKEL ADDNEELQRP
KCLLCPANFP IASLKKFIIY KYSIPTHLFY VEIMYKVHTI TLPDHYTLMD VAYIYTWKKD
AHMRFFYRIR THEMKSVELP EVPLRRSPSL SGAPGPRALA TIKEEDGTDC KDSATVELIK
PSDIKREQSV EGDSKQQQQQ TNSEVNTVVT EEVAPVVPVA PPKAVADVKP AREEPKVKKN
ESIKLKIEMT KNTYVSILQS PQMDAASKHH KSDRPEKVKK KKSEDKDRSV NKIKSTSDLK
IKIEKVKDGL VSVKKDGKSS KKVPYKVELS PGISDLKNNN LKIALNNEVD SKKAKKEAHK
LDKSQKKMKS PKRIPDFDKV QPSIVLKIDQ KSPELSTSML KIVSHPLASS SPKHKPETTI
EDEKSQFLNS FELTPIKSVN GGNTSRSPSS SPGSSASPPA TSAAEAKTAK RKMKESASGR
TVTKKPKLSD DEIKALVERT VQQNIKSTAE QIAPPPAVPS PPVKQEVLSP PAPVVEAPKP
NPLPVKTEST PKEAPKSESK PKPFDFKTPA VLPPPITTTN IPAPKPAQPV MIAPKPSAPE
SSKRPVPLFP KPIQPAKKLP PLLPKDVDYM KSNNKQKLME MKQRPTPLTI SPNKDTEISQ
IKPEDAGKNI KVYGPDADNF AVPAALPTIP TKPKSNKSRP VNYLNYALMN NNKVPAGSRT
PIPSYSNSPS YSPDSPQYNP NFNISTKQFK YANPLAYANH LQNMLNDRKT VSPPLAAPPQ
ERKPENERKR PCPSPDSKQE PLEKQPKVQS LLNQINIPSS LSITLATEED EAAREKARKS
MPEEDKNYIE ILKLPEISIT EADRATPPKV VEATGKKVSK SPSPTKGEKS KVEGKKFDAV
DKTSYQQKYV QSILDMKQRG NKSSNKVEKQ PAPVFTPPTS SPSAMNNSFK LPNATVLSNG
IVKLNSYPEL DLINKNSGGS PGSSSRPTPS PPKPSKHVPI APKPTGTFFP PTGTPHIPPP
QRKSLSPPVP KPLVSPIQPK SKTPPIVHSG SPSHAALAAM GPMFGIQMKP ESSGYSKKLQ
EPRPKKTSQK SPRSSNNNSL LDLSSSPTGP MSAATTAATT SPSAMDKAKE QAAAMNMLMM
NSNAQKQIHM NNYLTELAKL NNQNMMMPQM VGLQPNPVFN QMMQALYLQQ YCRMSKASSD
NLDK
//
